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A thermode-electrode for physiological studies of highly discrete tissue loci

A thermode-electrode for physiological studies of highly discrete tissue loci A thermode-electrode physiological studies of highly discrete tissue loci N. HERBERT Department SPECTOR Medical College of Virgin ;a, Richmond, Virginia 23219 of Physiology, J. Appl. Physiol. 27(5): 770-773. 1969.-A new design a combination thermode and monopolar electrode is described. It was used in behavioral studies heating or cooling discrete loci in the brains of rats and intracranial electrical self-stimulation, where the site of the electrical stimulus was also simultaneously heated or cooled. With size modifications, this design is applicable to other tissues and to most species. The thermode has the advantage of rapid heat transfer characteristics limited to a small tissue volume and may be used in acute experiments or in chronic implants several months with minimal tissue damage. It can also serve electrical recording, with or without concomitant thermal manipulation. brain cooling; brain heating; CNS, electrical stimulation of; CNS, thermal stimulation of; hyperthermia; hypothalamus; hypothermia; preoptic area; self-stimulation, intracranial; temperature regulation SPECTOR, N. HERBERT. studies of highly discrete tissue A loci. thermode-electrode physiological IN STARTING A SERIES of investigations on the relation of feeding behavior to diencephalic and body core temperatures, it was necessary to design a new thermode which could heat or cool much smaller and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

A thermode-electrode for physiological studies of highly discrete tissue loci

N. H. Spector
Journal of Applied Physiology , Volume 27: 770 – Nov 1, 1969
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Publisher
The American Physiological Society
Copyright
Copyright © 1969 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
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Abstract

A thermode-electrode physiological studies of highly discrete tissue loci N. HERBERT Department SPECTOR Medical College of Virgin ;a, Richmond, Virginia 23219 of Physiology, J. Appl. Physiol. 27(5): 770-773. 1969.-A new design a combination thermode and monopolar electrode is described. It was used in behavioral studies heating or cooling discrete loci in the brains of rats and intracranial electrical self-stimulation, where the site of the electrical stimulus was also simultaneously heated or cooled. With size modifications, this design is applicable to other tissues and to most species. The thermode has the advantage of rapid heat transfer characteristics limited to a small tissue volume and may be used in acute experiments or in chronic implants several months with minimal tissue damage. It can also serve electrical recording, with or without concomitant thermal manipulation. brain cooling; brain heating; CNS, electrical stimulation of; CNS, thermal stimulation of; hyperthermia; hypothalamus; hypothermia; preoptic area; self-stimulation, intracranial; temperature regulation SPECTOR, N. HERBERT. studies of highly discrete tissue A loci. thermode-electrode physiological IN STARTING A SERIES of investigations on the relation of feeding behavior to diencephalic and body core temperatures, it was necessary to design a new thermode which could heat or cool much smaller and

Journal

Journal of Applied Physiology – The American Physiological Society

Published: Nov 1, 1969

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