Yohimbine

Yohimbine Reactions 1704, p374 - 2 Jun 2018 Priapism following misuse: case report A 40-year-old man developed priapism misuse of yohimbine containing OTC for sexual dysfunction [ExtenZe; route not clearly stated]. The man, who had schizoaffective disorder, presented to the medical emergency department for sustained erection for three days. His medical history was significant for diabetes mellitus and a seizure disorder. He had been taking yohimbine containing OTC tablets daily for relieving his sexual dysfunction. He used to take more tablets than the recommended dose of one tablet daily which was considered misuse of the product. Physical examination showed a non- tender and fully erected penis. His other laboratory tests were normal except elevated white cell count and mature neutrophils. Subsequently, the man was admitted to the urology department for further treatment. He underwent a Winter’s shunt procedure which led to complete resolution of the priapism. He was discharged three days after the surgery on ciprofloxacin and oxycodone with acetaminophen. He was asked to continue his psychotropic medications. Author comment: "In this report, we describe a case of intractable priapism, which required definitive surgical intervention, related to misuse of OTC ExtenZe to address the sexual side effects of antipsychotics. To our knowledge, this is the first case of priapism resulting from the use of ExtenZe, the non–Food and Drug Administration–approved, alternative, herbal supplement". "ExtenZe also contains yohimbe, . . .marketed as an OTC sexual enhancer." Lee J, et al. The Risks of Using Herbal Supplements for Sexual Dysfunction Associated with Psychotropic Medications: A Case Report of ExtenZe Use and Priapism. Journal of Clinical Psychopharmacology 38: 274-275, No. 3, Jun 2018. Available from: URL: http://doi.org/10.1097/JCP.0000000000000857 - USA 803323791 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Yohimbine

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-47017-7
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p374 - 2 Jun 2018 Priapism following misuse: case report A 40-year-old man developed priapism misuse of yohimbine containing OTC for sexual dysfunction [ExtenZe; route not clearly stated]. The man, who had schizoaffective disorder, presented to the medical emergency department for sustained erection for three days. His medical history was significant for diabetes mellitus and a seizure disorder. He had been taking yohimbine containing OTC tablets daily for relieving his sexual dysfunction. He used to take more tablets than the recommended dose of one tablet daily which was considered misuse of the product. Physical examination showed a non- tender and fully erected penis. His other laboratory tests were normal except elevated white cell count and mature neutrophils. Subsequently, the man was admitted to the urology department for further treatment. He underwent a Winter’s shunt procedure which led to complete resolution of the priapism. He was discharged three days after the surgery on ciprofloxacin and oxycodone with acetaminophen. He was asked to continue his psychotropic medications. Author comment: "In this report, we describe a case of intractable priapism, which required definitive surgical intervention, related to misuse of OTC ExtenZe to address the sexual side effects of antipsychotics. To our knowledge, this is the first case of priapism resulting from the use of ExtenZe, the non–Food and Drug Administration–approved, alternative, herbal supplement". "ExtenZe also contains yohimbe, . . .marketed as an OTC sexual enhancer." Lee J, et al. The Risks of Using Herbal Supplements for Sexual Dysfunction Associated with Psychotropic Medications: A Case Report of ExtenZe Use and Priapism. Journal of Clinical Psychopharmacology 38: 274-275, No. 3, Jun 2018. Available from: URL: http://doi.org/10.1097/JCP.0000000000000857 - USA 803323791 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

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