Neuroinformatics (2018) 16:151–152 https://doi.org/10.1007/s12021-018-9378-9 OBITUARY Gordon M. Shepherd Published online: 23 May 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 Wilfrid Rall (August 29, 1922 – April 1, 2018) was one of a meeting held at Ojai, California, on new methods of the founders of modern neuroscience. Trained as a bio- theoretical brain science. In this article he laid out the physicist, he focused in the 1950s on the flow of electric compartmental method, in which segments of neuronal current in neurons, and proved that the dendritic current axons and dendrites were represented by equivalent circuits dominated the integration of synaptic inputs and the gen- that could simulate passive, synaptic, or active properties in eration of outputs. Ramon y Cajal (1852–1934) had pro- any arbitrary manner to test experimental results or predict vided the anatomical evidence for the elaborate structure new properties. of dendritic branching; Rall provided the rigorous func- Pioneered first on spinal motor neuron dendrites, the tional framework for understanding the role of the dendrit- Rall compartmental method was applied to brain neurons ic structures and their electrical properties in neuronal in the olfactory bulb, then extended by others in the 1970s function. to the
Neuroinformatics – Springer Journals
Published: May 23, 2018
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