Which organisms and technologies fall under the mutagenesis exemption of the European GMO-Directive?

Which organisms and technologies fall under the mutagenesis exemption of the European GMO-Directive? The European GMO-Directive’s (2001/18/EC) mutagenesis exemption may exempt organisms produced by genome editing from the legal obligations of the Directive, according to the recently published opinion of the Advocate General of the Court of Justice of the European Union (CJEU). We analyse his opinion and assess that the caveat in Art. 3(1) i.c.w. Annex 1B does not allow the use of nucleic acid vector constructs and CRISPR’s sgRNA. This represents an obstacle for genome editing in plants and animals, since most current setups use vectors. However, alternatives are under way. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal für Verbraucherschutz und Lebensmittelsicherheit Springer Journals

Which organisms and technologies fall under the mutagenesis exemption of the European GMO-Directive?

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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Bundesamt für Verbraucherschutz und Lebensmittelsicherheit (BVL)
Subject
Life Sciences; Life Sciences, general; Food Science; Biotechnology; Agriculture; Chemistry/Food Science, general; Plant Genetics and Genomics
ISSN
1661-5751
eISSN
1661-5867
D.O.I.
10.1007/s00003-018-1166-9
Publisher site
See Article on Publisher Site

Abstract

The European GMO-Directive’s (2001/18/EC) mutagenesis exemption may exempt organisms produced by genome editing from the legal obligations of the Directive, according to the recently published opinion of the Advocate General of the Court of Justice of the European Union (CJEU). We analyse his opinion and assess that the caveat in Art. 3(1) i.c.w. Annex 1B does not allow the use of nucleic acid vector constructs and CRISPR’s sgRNA. This represents an obstacle for genome editing in plants and animals, since most current setups use vectors. However, alternatives are under way.

Journal

Journal für Verbraucherschutz und LebensmittelsicherheitSpringer Journals

Published: Jun 1, 2018

References

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