Ventricular dyssynchrony assessment using ultra-high frequency ECG technique

Ventricular dyssynchrony assessment using ultra-high frequency ECG technique Purpose The aim of this proof-of-concept study is to intro- dyssynchrony distribution in resolution of milliseconds and duce new high-dynamic ECG technique with potential to de- correlate with strain rate results obtained by speckle tracking tect temporal-spatial distribution of ventricular electrical de- echocardiography. The effect of biventricular stimulation is polarization and to assess the level of ventricular demonstrated by the UHFQRS morphology and by the dyssynchrony. UHFDYS descriptor in selected examples. Methods 5-kHz 12-lead ECG data was collected. The ampli- Conclusions UHFQRS offers a new and simple technique for tude envelopes of the QRS were computed in an ultra-high assessing electrical activation patterns in ventricular frequency band of 500–1000 Hz and were averaged dyssynchrony with a temporal-spatial resolution that cannot (UHFQRS). UHFQRS V lead maps were compiled, and nu- be obtained by processing standard surface ECG. The main merical descriptor identifying ventricular dyssynchrony clinical potential of UHFQRS lies in the identification of dif- (UHFDYS) was detected. ferences in electrical activation among CRT candidates and detection of improvements in electrical synchrony in patients with biventricular pacing. Electronic supplementary material The online version of this article (doi:10.1007/s10840-017-0268-0) contains supplementary material, Keywords Ventricular dyssynchrony Cardiac which is available to authorized users. resynchronization Journal of Interventional Cardiac Electrophysiology Springer Journals

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Medicine & Public Health; Cardiology
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