Validation of the JCOG prognostic index in advanced gastric cancer using individual patient data from the SPIRITS and G-SOX trials

Validation of the JCOG prognostic index in advanced gastric cancer using individual patient data... Gastric Cancer (2017) 20:757–763 DOI 10.1007/s10120-017-0702-0 ORIGINAL ARTICLE Validation of the JCOG prognostic index in advanced gastric cancer using individual patient data from the SPIRITS and G-SOX trials 1 2 3 4 • • • • Daisuke Takahari Junki Mizusawa Wasaburo Koizumi Ichinosuke Hyodo Narikazu Boku Received: 25 December 2016 / Accepted: 5 February 2017 / Published online: 16 February 2017 The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2017 Abstract demonstrated highly significant survival differences; the Background In a phase III study for advanced gastric hazard ratios (95% confidence interval) were 1.71 cancer (AGC), the Japan Clinical Oncology Group (JCOG) (1.46–2.01) between the good (n = 338) and moderate 9912 trial, we previously identified the following four (n = 537) risk groups and 3.32 (2.47–4.46) between good prognostic factors—performance status C1, number of and poor (n = 61) risk groups. The median overall survival metastatic sites C2, no prior gastrectomy, and abnormal times of the good, moderate, and poor risk groups were serum alkaline phosphatase levels—and proposed a prog- 17.2, 12.0, and 7.8 months, respectively. nostic index (good risk with 0 or 1 factor, moderate risk Conclusions The JCOG prognostic index was externally with 2 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Gastric Cancer Springer Journals

Validation of the JCOG prognostic index in advanced gastric cancer using individual patient data from the SPIRITS and G-SOX trials

Loading next page...
 
/lp/springer_journal/validation-of-the-jcog-prognostic-index-in-advanced-gastric-cancer-OAnr334u80
Publisher
Springer Japan
Copyright
Copyright © 2017 by The International Gastric Cancer Association and The Japanese Gastric Cancer Association
Subject
Medicine & Public Health; Surgical Oncology; Oncology; Abdominal Surgery; Gastroenterology; Cancer Research
ISSN
1436-3291
eISSN
1436-3305
D.O.I.
10.1007/s10120-017-0702-0
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial