Using the fetal oxyhaemoglobin dissociation curve to calculate the ventilation/perfusion ratio and right to left shunt in healthy newborn infants

Using the fetal oxyhaemoglobin dissociation curve to calculate the ventilation/perfusion ratio... Journal of Clinical Monitoring and Computing https://doi.org/10.1007/s10877-018-0168-6 LE T TER TO  THE   EDITOR Using the fetal oxyhaemoglobin dissociation curve to calculate the ventilation/perfusion ratio and right to left shunt in healthy newborn infants 1 1 2 2,3 Theodore Dassios  · Kamal Ali  · Thomas Rossor  · Anne Greenough Received: 25 March 2017 / Accepted: 31 May 2018 © Springer Nature B.V. 2018 Oxygenation impairment can be non-invasively assessed by fetal ODC to the left, reflecting the higher affinity of fetal the degree of right-to-left shunt and ventilation/perfusion haemoglobin to oxygen [6]. Thus, had we utilised a fetal inequality. The relative rightwards displacement of an indi- curve we would have reported relatively higher values of vidual’s oxyhaemoglobin dissociation curve (ODC) can be shift and lower values of V /Q (Fig. 1). We chose the adult used to determine the reduction of the ventilation to perfu- haemoglobin because the relatively rapid rate of decline of sion ratio and the degree of depression of the ODC can be fetal haemoglobin after birth [7], would mean the neonatal used to quantify the level of right to left shunt (Fig. 1). Using curve would be shifting to the right during the first weeks, paired samples of peripheral oxygen saturation and fraction constituting a moving reference http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical Monitoring and Computing Springer Journals

Using the fetal oxyhaemoglobin dissociation curve to calculate the ventilation/perfusion ratio and right to left shunt in healthy newborn infants

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Nature B.V.
Subject
Medicine & Public Health; Anesthesiology; Intensive / Critical Care Medicine; Statistics for Life Sciences, Medicine, Health Sciences
ISSN
1387-1307
eISSN
1573-2614
D.O.I.
10.1007/s10877-018-0168-6
Publisher site
See Article on Publisher Site

Abstract

Journal of Clinical Monitoring and Computing https://doi.org/10.1007/s10877-018-0168-6 LE T TER TO  THE   EDITOR Using the fetal oxyhaemoglobin dissociation curve to calculate the ventilation/perfusion ratio and right to left shunt in healthy newborn infants 1 1 2 2,3 Theodore Dassios  · Kamal Ali  · Thomas Rossor  · Anne Greenough Received: 25 March 2017 / Accepted: 31 May 2018 © Springer Nature B.V. 2018 Oxygenation impairment can be non-invasively assessed by fetal ODC to the left, reflecting the higher affinity of fetal the degree of right-to-left shunt and ventilation/perfusion haemoglobin to oxygen [6]. Thus, had we utilised a fetal inequality. The relative rightwards displacement of an indi- curve we would have reported relatively higher values of vidual’s oxyhaemoglobin dissociation curve (ODC) can be shift and lower values of V /Q (Fig. 1). We chose the adult used to determine the reduction of the ventilation to perfu- haemoglobin because the relatively rapid rate of decline of sion ratio and the degree of depression of the ODC can be fetal haemoglobin after birth [7], would mean the neonatal used to quantify the level of right to left shunt (Fig. 1). Using curve would be shifting to the right during the first weeks, paired samples of peripheral oxygen saturation and fraction constituting a moving reference

Journal

Journal of Clinical Monitoring and ComputingSpringer Journals

Published: Jun 6, 2018

References

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