Journal of Clinical Monitoring and Computing https://doi.org/10.1007/s10877-018-0168-6 LE T TER TO THE EDITOR Using the fetal oxyhaemoglobin dissociation curve to calculate the ventilation/perfusion ratio and right to left shunt in healthy newborn infants 1 1 2 2,3 Theodore Dassios · Kamal Ali · Thomas Rossor · Anne Greenough Received: 25 March 2017 / Accepted: 31 May 2018 © Springer Nature B.V. 2018 Oxygenation impairment can be non-invasively assessed by fetal ODC to the left, reflecting the higher affinity of fetal the degree of right-to-left shunt and ventilation/perfusion haemoglobin to oxygen . Thus, had we utilised a fetal inequality. The relative rightwards displacement of an indi- curve we would have reported relatively higher values of vidual’s oxyhaemoglobin dissociation curve (ODC) can be shift and lower values of V /Q (Fig. 1). We chose the adult used to determine the reduction of the ventilation to perfu- haemoglobin because the relatively rapid rate of decline of sion ratio and the degree of depression of the ODC can be fetal haemoglobin after birth , would mean the neonatal used to quantify the level of right to left shunt (Fig. 1). Using curve would be shifting to the right during the first weeks, paired samples of peripheral oxygen saturation and fraction constituting a moving reference
Journal of Clinical Monitoring and Computing – Springer Journals
Published: Jun 6, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera