Urinary transcript quantitation of CK20 and IGF2 for the non-invasive bladder cancer detection

Urinary transcript quantitation of CK20 and IGF2 for the non-invasive bladder cancer detection J Cancer Res Clin Oncol (2017) 143:1757–1769 DOI 10.1007/s00432-017-2433-3 ORIGINAL ARTICLE – CANCER RESEARCH Urinary transcript quantitation of CK20 and IGF2 for the non‑invasive bladder cancer detection 1 1 2 2 2 Karsten Salomo · Doreen Huebner · Manja U. Boehme · Alexander Herr · Werner Brabetz · 1 3 3 4 4 Ulrike Heberling · Oliver W. Hakenberg · Daniela Jahn · Marc‑Oliver Grimm · Daniel Steinbach · 5 1 1 1 Marcus Horstmann · Michael Froehner · Manfred P. Wirth · Susanne Fuessel Received: 24 February 2017 / Accepted: 24 April 2017 / Published online: 8 May 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract 84.0%) were similar to that of VUC. The sensitivity of Purpose Cytokeratin 20 (CK20) and insulin-like growth VUC in combination with CK20 and IGF2 was consider- factor 2 (IGF2) were previously proposed to be elevated in ably increased (SN : 94.6; SN : 93.2%) while specificity TC VC clinical samples from patients with bladder cancer (BCa). was reduced (SP : 72.0; SP : 82.0%) compared to VUC TC VC A two cohort design validation study was used to assess the alone in the test and validation cohort. relevance for BCa detection by transcript http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Cancer Research and Clinical Oncology Springer Journals
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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Oncology; Cancer Research; Internal Medicine; Hematology
ISSN
0171-5216
eISSN
1432-1335
D.O.I.
10.1007/s00432-017-2433-3
Publisher site
See Article on Publisher Site

Abstract

J Cancer Res Clin Oncol (2017) 143:1757–1769 DOI 10.1007/s00432-017-2433-3 ORIGINAL ARTICLE – CANCER RESEARCH Urinary transcript quantitation of CK20 and IGF2 for the non‑invasive bladder cancer detection 1 1 2 2 2 Karsten Salomo · Doreen Huebner · Manja U. Boehme · Alexander Herr · Werner Brabetz · 1 3 3 4 4 Ulrike Heberling · Oliver W. Hakenberg · Daniela Jahn · Marc‑Oliver Grimm · Daniel Steinbach · 5 1 1 1 Marcus Horstmann · Michael Froehner · Manfred P. Wirth · Susanne Fuessel Received: 24 February 2017 / Accepted: 24 April 2017 / Published online: 8 May 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract 84.0%) were similar to that of VUC. The sensitivity of Purpose Cytokeratin 20 (CK20) and insulin-like growth VUC in combination with CK20 and IGF2 was consider- factor 2 (IGF2) were previously proposed to be elevated in ably increased (SN : 94.6; SN : 93.2%) while specificity TC VC clinical samples from patients with bladder cancer (BCa). was reduced (SP : 72.0; SP : 82.0%) compared to VUC TC VC A two cohort design validation study was used to assess the alone in the test and validation cohort. relevance for BCa detection by transcript

Journal

Journal of Cancer Research and Clinical OncologySpringer Journals

Published: May 8, 2017

References

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