Update on Allergen Immunotherapy for Allergic Rhinitis: Drops, Tablets, or Shots?

Update on Allergen Immunotherapy for Allergic Rhinitis: Drops, Tablets, or Shots? Curr Otorhinolaryngol Rep (2017) 5:181–186 DOI 10.1007/s40136-017-0159-z SPECIAL TOPICS IN OTORHINOLARYNGOLOGY: OTOLARYNGIC ALLERGY (E TOSKALA, SECTION EDITOR) Update on Allergen Immunotherapy for Allergic Rhinitis: Drops, Tablets, or Shots? 1 1 Christopher R. Roxbury & Sandra Y. Lin Published online: 20 July 2017 Springer Science+Business Media, LLC 2017 Abstract Keywords Allergic rhinitis Allergen-specific . . Purpose of Review Allergen immunotherapy (AIT) is the only immunotherapy Sublingual immunotherapy Subcutaneous disease-modifying treatment available for allergic rhinitis immunotherapy Intralymphatic immunotherapy (AR). Dosing considerations, efficacy, and safety of subcuta- neous (SCIT), sublingual (SLIT), and intralymphatic (ILIT) immunotherapy are discussed. Introduction Recent Findings Patients with AR who cannot tolerate or do not wish to continue indefinite pharmacotherapy may be can- Allergic rhinitis (AR) is a common condition mediated by didates for AIT. SCIT is the gold standard formulation but type-1 hypersensitivity reactions that has a prevalence of requires repeat injections over several years and may place 10–30% in adults and as many as 40% of children [1, 2]. the patient at risk for systemic allergic reactions such as ana- Symptoms are related to local release of histamine, and com- phylaxis. SLIT has been developed as an alternative formula- monly include nasal congestion, sneezing, rhinorrhea, and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Otorhinolaryngology Reports Springer Journals

Update on Allergen Immunotherapy for Allergic Rhinitis: Drops, Tablets, or Shots?

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Otorhinolaryngology
eISSN
2167-583X
D.O.I.
10.1007/s40136-017-0159-z
Publisher site
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