Curr Otorhinolaryngol Rep (2017) 5:181–186 DOI 10.1007/s40136-017-0159-z SPECIAL TOPICS IN OTORHINOLARYNGOLOGY: OTOLARYNGIC ALLERGY (E TOSKALA, SECTION EDITOR) Update on Allergen Immunotherapy for Allergic Rhinitis: Drops, Tablets, or Shots? 1 1 Christopher R. Roxbury & Sandra Y. Lin Published online: 20 July 2017 Springer Science+Business Media, LLC 2017 Abstract Keywords Allergic rhinitis Allergen-specific . . Purpose of Review Allergen immunotherapy (AIT) is the only immunotherapy Sublingual immunotherapy Subcutaneous disease-modifying treatment available for allergic rhinitis immunotherapy Intralymphatic immunotherapy (AR). Dosing considerations, efficacy, and safety of subcuta- neous (SCIT), sublingual (SLIT), and intralymphatic (ILIT) immunotherapy are discussed. Introduction Recent Findings Patients with AR who cannot tolerate or do not wish to continue indefinite pharmacotherapy may be can- Allergic rhinitis (AR) is a common condition mediated by didates for AIT. SCIT is the gold standard formulation but type-1 hypersensitivity reactions that has a prevalence of requires repeat injections over several years and may place 10–30% in adults and as many as 40% of children [1, 2]. the patient at risk for systemic allergic reactions such as ana- Symptoms are related to local release of histamine, and com- phylaxis. SLIT has been developed as an alternative formula- monly include nasal congestion, sneezing, rhinorrhea, and
Current Otorhinolaryngology Reports – Springer Journals
Published: Jul 20, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera