Update of Hepatitis C in Colombia

Update of Hepatitis C in Colombia Purpose of Review The goal is to describe the epidemiology, disease burden and detection, available therapies, and current challenges to access care for people with chronic hepatitis C infection in Colombia. Recent Findings There are no detailed statistics about the prevalence of HCV in Colombia; nonetheless, majority of patients with hepatitis C are infected with genotype 1 and having received blood products before 1996 represents the main risk factor. The use of intravenous drugs has started to be recognized as a population at risk that is in increment. Direct-acting antivirals became available in 2016 in Colombia thanks to a centralized purchase program with the Pan American Health Organization. Summary There are well-established guidelines for the use of available antivirals for all disease stages and genotypes and sustained virologic response (SVR) rates are 95 to 100%. Underdiagnosis, access and linkage to care, and disease stigmatization have contributed to a low number of patients that have actually completed their therapy. . . . . . Keywords Hepatitis C HCV Colombia South America Direct-acting antiviral DAA Introduction 22% since 2000. These deaths have been related to chronic complications such as cirrhosis (± 280,000 deaths) and hepa- Worldwide, the amount of annual deaths http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Tropical Medicine Reports Springer Journals
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Tropical Medicine; Parasitology; Behavioral Sciences; Infectious Diseases
eISSN
2196-3045
D.O.I.
10.1007/s40475-018-0147-5
Publisher site
See Article on Publisher Site

Abstract

Purpose of Review The goal is to describe the epidemiology, disease burden and detection, available therapies, and current challenges to access care for people with chronic hepatitis C infection in Colombia. Recent Findings There are no detailed statistics about the prevalence of HCV in Colombia; nonetheless, majority of patients with hepatitis C are infected with genotype 1 and having received blood products before 1996 represents the main risk factor. The use of intravenous drugs has started to be recognized as a population at risk that is in increment. Direct-acting antivirals became available in 2016 in Colombia thanks to a centralized purchase program with the Pan American Health Organization. Summary There are well-established guidelines for the use of available antivirals for all disease stages and genotypes and sustained virologic response (SVR) rates are 95 to 100%. Underdiagnosis, access and linkage to care, and disease stigmatization have contributed to a low number of patients that have actually completed their therapy. . . . . . Keywords Hepatitis C HCV Colombia South America Direct-acting antiviral DAA Introduction 22% since 2000. These deaths have been related to chronic complications such as cirrhosis (± 280,000 deaths) and hepa- Worldwide, the amount of annual deaths

Journal

Current Tropical Medicine ReportsSpringer Journals

Published: Jun 4, 2018

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