Curr Fungal Infect Rep (2017) 11:84–91 DOI 10.1007/s12281-017-0288-3 CURRENT MANAGEMENT OF FUNGAL INFECTIONS (M MICELI, SECTION EDITOR) Untargeted Antifungal Treatment Strategies for Invasive Candidiasis in Non-neutropenic Critically Ill Patients: Current Evidence and Insights 1 1 1 Andrea Cortegiani & Vincenzo Russotto & Santi Maurizio Raineri & 1 2 1 Cesare Gregoretti & Francesco Giuseppe De Rosa & Antonino Giarratano Published online: 22 July 2017 Springer Science+Business Media, LLC 2017 . . Abstract Keywords Invasive candidiasis Invasive fungal infection . . . Purpose of Review The purpose of this study was to pro- Candida infection Candidemia Empiric treatment vide an overview and insights on important new concepts Antifungal treatment on untargeted antifungal treatment strategies, namely pro- phylaxis pre-emptive and empiric treatments for the man- agement of invasive candidiasis (IC) in non-neutropenic Introduction critically ill patients. Recent Findings Recently, clinical practice guidelines provid- Invasive candidiasis (IC) is a major cause of morbidity and ed recommendation for the management of IC. However, re- mortality in critically ill patients . Critically ill patients have sults from recent trials and systematic reviews questioned the several risk factors for IC development such as broad- effect of untargeted antifungal treatment strategies, especially spectrum antibiotic treatment, disruption
Current Fungal Infection Reports – Springer Journals
Published: Jul 22, 2017
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