Ultrasonographic and histopathologic changes following injection of neutral zinc gluconate in dog’s ovaries

Ultrasonographic and histopathologic changes following injection of neutral zinc gluconate in... Different methods of fertility control are established in order to control the population of dogs and one of them is chemical methods. The effects of zinc gluconate on dog’s ovaries were studied. In this study, four female healthy and fertile dogs were selected randomly. Under general anesthesia and during laparotomy, the neutral sterile zinc gluconate was injected directly into the ovaries of five dogs. Changes in the size and appearance of the ovaries, leukocytes, and vaginal cytology were monitored before and after the start of the study twice a week. After 1 month, the uterus and ovaries were removed surgically and sent to laboratory for histopathologic examination. Except one dog which was in diestrus, the other dogs were in anestrus during the study. Based on ultrasonographic examination, zinc gluconate injection reduced the diameter of the ovaries after 1 month (P < 0.05). A significant reduction in the number of leukocytes occurred from the second day until the third day (P < 0.05). By the end of the study, decreases in the percentage of leukocytes were almost constant. In the histopathological examination, hyperemia was observed, and atretic, primordial, and primary follicles; fibrosis; and hemosiderin pigment were found in the ovaries. Consequently, the injection of neutral zinc gluconate did not destroy all ovarian structures after 1 month. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Comparative Clinical Pathology Springer Journals

Ultrasonographic and histopathologic changes following injection of neutral zinc gluconate in dog’s ovaries

Loading next page...
Springer London
Copyright © 2017 by Springer-Verlag London
Medicine & Public Health; Pathology; Hematology; Oncology
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial