Mammalian Genome 9, 331-333 (1998). Mammalian Genome Incorpornlinq V/ou^v frnum^ Springer-Verlag New York Inc. 1998 Twelve genes, including the unassigned proteasome subunit gene, ordered within the human 1p13 region Veronique Mayau, Bruno Baron, Gerard Buttin, Michelle Debatisse Unite de Genetique Somatique (URA CNRS 1960), Institut Pasteur, 25 rue du Dr. Roux, F-75724 Paris Cedex 15, France Received: 9 October 1997 / Accepted: 25 November 1997 Using a coamplification mapping technique, we previously estab- were not ordered with respect to one another in this experiment. lished the map of a cluster of genes located on Chinese hamster However, the fact that the GSTM1 and GSTM2 cDNAs share a Chromosome (Chr) lq. It was shown that the gene coding the remarkable 99% identity and that the GSTMI allele is deleted in adenosine monophosphate deaminase2 is flanked on one (AMPD2) half the adult population (Board 1981) suggested that the frequent side by members of the glutathione S-transferase p. family genes deletion of the GSTMI gene results from unequal, but homologous (GSTM), and on the other side by the genes encoding the c t2 and recombination events occurring between the two genes (Pearson et the csi3 subunits of the G proteins (GNAT2 and
Mammalian Genome – Springer Journals
Published: Mar 20, 2009
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