Breslow thickness is the only variable that is consistently reported as an independent predictor of SLN status. The use of TMR and ulceration in staging criteria is intended to establish prognosis, not select for SLNB. Given the important implications of a positive SLNB on surgical management, accurate selection is imperative. Selection based solely on Breslow thickness, rather than staging criteria, may be valid. However, there is an urgent need for a well-designed large multi-centre analysis to validate this. Until then, we continue to select for SLNB within a multidisciplinary team accounting for multiple factors. Level of Evidence: Level II, Prognostic/Risk Study.
European Journal of Plastic Surgery – Springer Journals
Published: Oct 1, 2012
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