Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer

Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer Ann Surg Oncol (2018) 25:2083–2090 https://doi.org/10.1245/s10434-018-6480-z O R I G IN AL ARTI CL E – TRAN SLATIO NA L R ESEA RCH AN D B IOM A RK ERS Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer Koichi Sawaki, MD, Mitsuro Kanda, MD, PhD, FACS, Takashi Miwa, MD, Shinichi Umeda, MD, Haruyoshi Tanaka, MD, Chie Tanaka, MD, PhD, Daisuke Kobayashi, MD, PhD, Masaya Suenaga, MD, PhD, Norifumi Hattori, MD, PhD, Masamichi Hayashi, MD, PhD, Suguru Yamada, MD, PhD, FACS, Goro Nakayama, MD, PhD, Michitaka Fujiwara, MD, PhD, and Yasuhiro Kodera, MD, PhD, FACS Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan ABSTRACT correlation coefficient[ 0.7. The optimal cutoff of TNNI2 Background. Although peritoneal metastasis is a serious expression was determined as 0.00017. High TNNI2 concern in patients with gastric cancer, no acceptable and expression was significantly and specifically associated specific biomarker is available. We aimed to identify a with peritoneal metastasis and served as an independent candidate biomarker to predict peritoneal metastasis of risk marker for peritoneal recurrence after curative gas- gastric cancer. trectomy. Prevalence of peritoneal recurrence increased in Methods. Metastatic pathway-specific transcriptome parallel with http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Surgical Oncology Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Society of Surgical Oncology
Subject
Medicine & Public Health; Surgical Oncology; Oncology; Surgery
ISSN
1068-9265
eISSN
1534-4681
D.O.I.
10.1245/s10434-018-6480-z
Publisher site
See Article on Publisher Site

Abstract

Ann Surg Oncol (2018) 25:2083–2090 https://doi.org/10.1245/s10434-018-6480-z O R I G IN AL ARTI CL E – TRAN SLATIO NA L R ESEA RCH AN D B IOM A RK ERS Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer Koichi Sawaki, MD, Mitsuro Kanda, MD, PhD, FACS, Takashi Miwa, MD, Shinichi Umeda, MD, Haruyoshi Tanaka, MD, Chie Tanaka, MD, PhD, Daisuke Kobayashi, MD, PhD, Masaya Suenaga, MD, PhD, Norifumi Hattori, MD, PhD, Masamichi Hayashi, MD, PhD, Suguru Yamada, MD, PhD, FACS, Goro Nakayama, MD, PhD, Michitaka Fujiwara, MD, PhD, and Yasuhiro Kodera, MD, PhD, FACS Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan ABSTRACT correlation coefficient[ 0.7. The optimal cutoff of TNNI2 Background. Although peritoneal metastasis is a serious expression was determined as 0.00017. High TNNI2 concern in patients with gastric cancer, no acceptable and expression was significantly and specifically associated specific biomarker is available. We aimed to identify a with peritoneal metastasis and served as an independent candidate biomarker to predict peritoneal metastasis of risk marker for peritoneal recurrence after curative gas- gastric cancer. trectomy. Prevalence of peritoneal recurrence increased in Methods. Metastatic pathway-specific transcriptome parallel with

Journal

Annals of Surgical OncologySpringer Journals

Published: Apr 16, 2018

References

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