Intensive Care Med (2017) 43:1413–1414 DOI 10.1007/s00134-017-4862-5 IM AGING IN INTENSIVE C ARE MEDICINE Trichosporon inkin disseminated infection 1 2 2 1* Laurie‑Anne Thion , Aymeric Coutard , Odile Eloy and Fabrice Bruneel © 2017 Springer‑ Verlag GmbH Germany and ESICM During the treatment of an acute lymphoblastic leukemia, inkin was identified by MALDI-TOF mass spectrometry a 40-year-old man developed a fever and was admitted to in both samples and in pleural fluid. Fundoscopy revealed the intensive care unit because of septic shock and respir- bilateral chorioretinitis, but transesophageal echocardi- atory failure. He presented with metastatic skin lesions ography did not find endocarditis. The patient received (Fig. 1a), and a computed tomography found diffuse prolonged intravenous voriconazole, and his condition pulmonary micronodules (Fig. 1b). Two blood cultures slowly improved. grew on the fourth day and direct microscopic examina- In recent years, Trichosporon has emerged as an tion showed fungal hyphae (Fig. 2a). The culture of the important opportunistic pathogen in immunocom- skin punch identified arthroconidia and blastoconidia promised individuals. As this yeast is resistant to echi- (Fig. 2b) suggesting Trichosporon species. Trichosporon nocandins and flucytosine, and considering that poor Fig. 1 Clinical and imaging findings. a Forearm skin lesion
Intensive Care Medicine – Springer Journals
Published: Jun 13, 2017
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