Curr Diab Rep (2017) 17: 127 https://doi.org/10.1007/s11892-017-0960-6 MICROVASCULAR COMPLICATIONS—NEUROPATHY (R POP-BUSUI, SECTION EDITOR) Christopher H. Gibbons Published online: 24 October 2017 Springer Science+Business Media, LLC 2017 Abstract Introduction Purpose of Review Treatment-induced neuropathy of diabetes (TIND) is an under-recognized iatrogenic painful sensory and In 1933, Charles Caravati described a case of a woman that autonomic neuropathy. This review highlights the clinical developed severe burning pain after initiating treatment with symptoms and signs, raises awareness of the cause, and insulin . The insulin was discontinued and the pain provides education about prevention of TIND. resolved. Pain returned though when insulin was resumed. Recent Findings TIND may be triggered by a rapid decline in He presumed that the problem was an allergic reaction to the blood glucose levels following the use of insulin, oral the insulin, so he described the case as “insulin neuritis.” hypoglycemic medications, or even diet only to control The name has persisted over the last 80 years and a handful of diabetes. This may be seen in up to 10% of patients with case reports have described similar problems, typically the diabetic neuropathy and has the potential for significant acute onset of severe pain in the setting
Current Diabetes Reports – Springer Journals
Published: Oct 24, 2017
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