Ir J Med Sci (2017) 186:589–595 DOI 10.1007/s11845-017-1594-z ORIGINAL ARTICLE Transformed follicular lymphoma (tFL): consolidation therapy may improve survival 1,2 2,3 1,2 1,2 1,2 • • • • • E. Elhassadi R. Flavin P. Browne E. Conneally P. Hayden 4 1 1,2 • • F. Quinn E. Higgins E. Vandenberghe Received: 30 August 2016 / Accepted: 2 March 2017 / Published online: 21 March 2017 Royal Academy of Medicine in Ireland 2017 Abstract presented with stage III/IV disease. Thirteen (50%) patients Purpose Retrospective study to evaluate the outcome of presented with de novo tFL and the remainder had previ- patients with transformed follicular lymphoma (tFL) trea- ously diagnosed FL, with a median time to transformation ted with rituximab-containing chemotherapy and of 5.7 (range 1–15) years. The median follow-up time from consolidation. tFL diagnosis to December 2015 is 8 (range 4–14) years. Patients and methods Patients diagnosed with tFL from All patients received immuno-chemotherapy achieving an 2003 to 2013 treated with consolidation therapy with last overall response rate (ORR) of 100%. Fourteen (54%), follow-up in December 2015 were identiﬁed from the patients were transplant eligible and based on donor institutional lymphoma database and included in this study. availability, six had
Irish Journal of Medical Science (1971 -) – Springer Journals
Published: Mar 21, 2017
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