Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Kozak (1989)
The scanning model for translation: an updateThe Journal of Cell Biology, 108
Qiang Xu, B. Modrek, Christopher Lee (2002)
Genome-wide detection of tissue-specific alternative splicing in the human transcriptome.Nucleic acids research, 30 17
Hanqing Xie, Weiguo. Zhu, A. Wasserman, Vladimir Grebinskiy, Andrew Olson, Liat Mintz (2002)
Computational analysis of alternative splicing using EST tissue information.Genomics, 80 3
Maruyama Kazuo, Sugano Sumio (1994)
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.Gene, 138 1-2
B. Schaefer (1995)
Revolutions in rapid amplification of cDNA ends: new strategies for polymerase chain reaction cloning of full-length cDNA ends.Analytical biochemistry, 227 2
Hiroyuki Takei, Y. Iino, J. Horiguchi, T. Kanoh, Y. Takao, T. Oyama, Yasuo Morishita (1995)
Immunohistochemical analysis of cytokeratin #8 as a prognostic factor in invasive breast carcinoma.Anticancer research, 15 3
Y. Tanaka, Hiroshi Kobayashi, Mika Suzuki, N. Kanayama, Mitsuaki Suzuki, Toru Yamakawa, H. Morishita, T. Terao (2003)
Reduced bikunin gene expression as a factor of poor prognosis in ovarian carcinomaCancer, 98
G. Berx, K. Becker, H. Höfler, F. Roy (1998)
Mutations of the human E‐cadherin (CDH1) geneHuman Mutation, 12
K. Graven, Q. Yu, D. Pan, J. Roncarati, H. Farber (1999)
Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene.Biochimica et biophysica acta, 1447 2-3
W. Bruening, N. Bardeesy, B. Silverman, R. Cohn, G. Machin, A. Aronson, D. Housman, J. Pelletier (1992)
Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital developmentNature Genetics, 1
Hiroyuki Orita, Y. Maehara, Y. Emi, Y. Kakeji, H. Baba, D. Korenaga, K. Sugimachi (1997)
c-erbB-2 expression is predictive for lymphatic spread of clinical gastric carcinoma.Hepato-gastroenterology, 44 13
D. Karan, D. Kelly, A. Rizzino, M. Lin, S. Batra (2002)
Expression profile of differentially-regulated genes during progression of androgen-independent growth in human prostate cancer cells.Carcinogenesis, 23 6
Nargis Nasrin, Louis Ercolani, Maria Denaro, X. Kong, Inwha Kang, Maria ALEXANDERt, Howard (1990)
An insulin response element in the glyceraldehyde-3-phosphate dehydrogenase gene binds a nuclear protein induced by insulin in cultured cells and by nutritional manipulations in vivo.Proceedings of the National Academy of Sciences of the United States of America, 87
Chuck Chao, Wing-Cheong Yam, Sue Lin-Chao (1990)
Coordinated induction of two unrelated glucose-regulated protein genes by a calcium ionophore: human BiP/GRP78 and GAPDH.Biochemical and biophysical research communications, 171 1
Kato. Seishi, Sekine Shingo, Oh Su-Wan, Kim, Nam-Soon, Umezawa Yuri, Abe Naoto, Yokoyama Midori, Aoki Takashi (1994)
Construction of a human full-length cDNA bank.Gene, 150 2
J. Broers, F. Ramaekers, M. Rot, T. Oostendorp, A. Huysmans, G. Muijen, S. Wagenaar, G. Vooijs (1988)
Cytokeratins in different types of human lung cancer as monitored by chain-specific monoclonal antibodies.Cancer research, 48 11
A. Hüttenhofer, M. Kiefmann, S. Meier-Ewert, J. O'Brien, H. Lehrach, J. Bachellerie, J. Brosius (2001)
RNomics: an experimental approach that identifies 201 candidates for novel, small, non‐messenger RNAs in mouseThe EMBO Journal, 20
M. Marra, L. Hillier, T. Kucaba, Melissa Allen, R. Barstead, C. Beck, Angela Blistain, M. Bonaldo, Yvette Bowers, L. Bowles, M. Cardenas, Ann Chamberlain, Julie Chappell, S. Clifton, A. Favello, Steve Geisel, Marilyn Gibbons, Njata Harvey, F. Hill, Yolanda Jackson, Sophie Kohn, G. Lennon, E. Mardis, John Martin, LeeAnne Mila, Rhonda McCann, Richard Morales, Deana Pape, B. Person, C. Prange, Erika Ritter, M. Soares, Rebecca Schurk, Tanya Shin, Michele Steptoe, T. Swaller, Brenda Theising, K. Underwood, T. Wylie, T. Yount, Richard Wilson, R. Waterston (1999)
An encyclopedia of mouse genesNature Genetics, 21
Jeong-Min Kim, H. Sohn, S. Yoon, Jung-Hwa Oh, Jin Yang, Joo Kim, K. Song, Seung-Moo Rho, H. Yoo, Y. Kim, Jong-Guk Kim, Nam-Soon Kim (2005)
Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells.Clinical cancer research : an official journal of the American Association for Cancer Research, 11 2 Pt 1
D. Brett, J. Hanke, G. Lehmann, Santiago Haase, S. Delbrück, S. Krueger, J. Reich, P. Bork (2000)
EST comparison indicates 38% of human mRNAs contain possible alternative splice formsFEBS Letters, 474
S. McKnight, R. Kingsbury (1982)
Transcriptional control signals of a eukaryotic protein-coding gene.Science, 217 4557
C. Benjamin, I. Dougas, G. Chi‐Rosso, S. Luhowskyj, M. Rosa, B. Newman, Laurelee Osborn, C. Vassallo, C. Hession, S. Goelz, Kathy McCarthy, R. Lobb (1990)
A blocking monoclonal antibody to endothelial-leukocyte adhesion molecule-1 (ELAM1).Biochemical and biophysical research communications, 171 1
Gene Yeo, D. Holste, Gabriel Kreiman, C. Burge (2004)
Variation in alternative splicing across human tissuesGenome Biology, 5
C. Novina, Ananda Roy (1996)
Core promoters and transcriptional control.Trends in genetics : TIG, 12 9
M. Soares, M. Bonaldo, P. Jelene, Long Su, L. Lawton, A. Efstratiadis (1994)
Construction and characterization of a normalized cDNA library.Proceedings of the National Academy of Sciences of the United States of America, 91 20
J. Kelley, J. Gocayne, M. Dubnick, Hong Xiao, Carl Merril, Andrew Wu, Bjorn Olde, Ruben Moreno, A. Kerlavage, W. McCombie (1991)
Complementary DNA sequencing: expressed sequence tags and human genome projectScience, 252
K. Oien, K. Oien, J. Vass, I. Downie, G. Fullarton, W. Keith (2003)
Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomachOncogene, 22
P. Kapranov, S. Cawley, J. Drenkow, S. Bekiranov, R. Strausberg, S. Fodor, T. Gingeras (2002)
Large-Scale Transcriptional Activity in Chromosomes 21 and 22Science, 296
Jung-Hwa Oh, H. Sohn, Jeong-Min Kim, Y. Kim, Nam-Soon Kim (2004)
Construction of multi-purpose vectors, pCNS and pCNS-D2, are suitable for collection and functional study of large-scale cDNAs.Plasmid, 51 3
K. Graven, R. Troxler, H. Kornfeld, M. Panchenko, H. Farber (1994)
Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia.The Journal of biological chemistry, 269 39
Nam-Soon Kim, Y. Hahn, Jung-Hwa Oh, Ju-Yeon Lee, K. Oh, Jeong-Min Kim, Hong-Seog Park, Sangsoo Kim, K. Song, Seung-Moo Rho, H. Yoo, Y. Kim (2004)
Gene cataloging and expression profiling in human gastric cancer cells by expressed sequence tags.Genomics, 83 6
Mika Suzuki, Hiroshi Kobayashi, Y. Tanaka, Y. Hirashima, N. Kanayama, Y. Takei, Y. Saga, Mitsuaki Suzuki, H. Itoh, T. Terao (2001)
Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikuninInternational Journal of Cancer, 104
E. Tahara (1995)
Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosisCancer, 75
Byungsik Kim, Seunghyun Bang, Seungkoo Lee, Soonok Kim, Yusun Jung, Changhee Lee, Kyungho Choi, Seong-Gene Lee, K. Lee, Yongsung Lee, Sang-Soo Kim, Y. Yeom, Yong-Sung Kim, H. Yoo, K. Song, Inchul Lee (2003)
Expression profiling and subtype-specific expression of stomach cancer.Cancer research, 63 23
Yen‐Hua Huang, Yu-Tin Chen, Jiunn-Jei Lai, S.-T. Yang, Ueng-Cheng Yang (2002)
PALS db: Putative Alternative Splicing databaseNucleic acids research, 30 1
L. Hillier, G. Lennon, M. Becker, M. Bonaldo, B. Chiapelli, S. Chissoe, N. Dietrich, T. DuBuque, A. Favello, W. Gish, M. Hawkins, M. Hultman, T. Kucaba, M. Lacy, M. Le, N. Le, E. Mardis, B. Moore, M. Morris, J. Parsons, C. Prange, L. Rifkin, T. Rohlfing, K. Schellenberg, M. Soares, F. Tan, J. Thierry-Meg, E. Trevaskis, K. Underwood, P. Wohldman, R. Waterston, R. Wilson, M. Marra (1996)
Generation and analysis of 280,000 human expressed sequence tags.Genome research, 6 9
K. Fukai, O. Yokosuka, T. Chiba, Y. Hirasawa, Motohisa Tada, F. Imazeki, H. Kataoka, H. Saisho (2003)
Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma.Cancer research, 63 24
Michael Clemens, U. Bommer (1999)
Translational control: the cancer connection.The international journal of biochemistry & cell biology, 31 1
M. Adams, A. Kerlavage, R. Flieschmann, R. Fuldner, C. Bult, N. Lee, E. Kirkness, K. Weinstock, J. Gocayne, O. White, G. Sutton, J. Blake, R. Brandon, M. Chiu, R. Clayton, R. Cline, M. Cotton, J. Earle-Hughes, L. Fine, Leah Fitzgerald, W. Fitzhugh, J. Fritchman, N. Geoghagen, A. Glodek, C. Gnehm, C. Venter (1995)
Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.Nature, 377 6547 Suppl
A. Velden, Adri Thomas (1999)
The role of the 5' untranslated region of an mRNA in translation regulation during development.The international journal of biochemistry & cell biology, 31 1
P. Mitchell, R. Tjian (1989)
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins.Science, 245 4916
A. Philips, L. Timchenko, T. Cooper (1998)
Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy.Science, 280 5364
A. Berk, P. Sharp (1977)
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybridsCell, 12
H. Kang, Il-Jin Kim, Jae‐Hyun Park, Y. Shin, J. Ku, M. Jung, B. Yoo, H. Kim, Jae‐Gahb Park (2004)
Identification of Genes with Differential Expression in Acquired Drug-Resistant Gastric Cancer Cells Using High-Density Oligonucleotide MicroarraysClinical Cancer Research, 10
A. Mironov, J. Fickett, M. Gelfand (1999)
Frequent alternative splicing of human genes.Genome research, 9 12
Jonathan Epstein, T. Glaser, Jiexing Cai, L. Jepeal, D. Walton, R. Maas (1994)
Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing.Genes & development, 8 17
Won-Sang Park, Ro Oh, J. Park, S. Lee, M. Shin, Y. Kim, S. Kim, H. Lee, P. Kim, S. Oh, N. Yoo, Jung Lee (1999)
Frequent somatic mutations of the beta-catenin gene in intestinal-type gastric cancer.Cancer research, 59 17
B. Modrek, Christopher Lee (2002)
A genomic view of alternative splicingNature Genetics, 30
Y. Fukunaga, S. Bandoh, J. Fujita, Yu Yang, Y. Ueda, S. Hojo, K. Dohmoto, Yasunori Tojo, J. Takahara, T. Ishida (2002)
Expression of cytokeratin 8 in lung cancer cell lines and measurement of serum cytokeratin 8 in lung cancer patients.Lung cancer, 38 1
Shinya Uchino, Hitoshi Tsuda, M. Noguchi, Jun Yokota, Masaaki Terada, Takao Saito, Michio Kobayashi, Takashi Sugimura, Setsuo Hirohashi (1992)
Frequent loss of heterozygosity at the DCC locus in gastric cancer.Cancer research, 52 11
Ji-yeon Lee, Eun-Mi Eom, Dae Kim, Y. Ha-Lee, Dong-Hee Lee (2003)
Analysis of gene expression profiles of gastric normal and cancer tissues by SAGE.Genomics, 82 1
Zhining Wang, H. Lo, Howard Yang, Sheryl Gere, Ying Hu, K. Buetow, M. Lee (2003)
Computational analysis and experimental validation of tumor-associated alternative RNA splicing in human cancer.Cancer research, 63 3
Yutaka Suzuki, Daisuke Ishihara, M. Sasaki, Haruhito Nakagawa, H. Hata, T. Tsunoda, Manabu Watanabe, Takami Komatsu, T. Ota, T. Isogai, A. Suyama, S. Sugano (2000)
Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries.Genomics, 64 3
H. Yokozaki, W. Yasui, E. Tahara (2001)
Genetic and epigenetic changes in stomach cancer.International review of cytology, 204
M. Yamauchi, H. Kataoka, H. Itoh, T. Seguchi, Yoshiniro Hasui, Y. Osada (2004)
Hepatocyte growth factor activator inhibitor types 1 and 2 are expressed by tubular epithelium in kidney and down-regulated in renal cell carcinoma.The Journal of urology, 171 2 Pt 1
To elucidate the genetic events associated with gastric cancer, 124,704 cDNA clones were collected from 37 human gastric cDNA libraries, including 20 full-length enriched cDNA libraries of gastric cancer cell lines and tissues from Korean patients. An analysis of the collected ESTs revealed that 97,930 high-quality ESTs coalesced into 13,001 clusters, of which 11,135 clusters (85.6%) were annotated to known ESTs. The analysis of the full-length cDNAs also revealed that 4862 clusters (51.7%) contained at least one putative full-length cDNA clone with an initiation codon, with the average length of the 5′ UTR of 140 bp. A large number appear to have a diverse transcription start site (TSS). An examination of the TSS of some genes, such as TEGT and GAPD, using 5′ RACE revealed that the predicted TSSs are actually found in human gastric cancer cells and that several TSSs differ depending on the specific gastric cell line. Furthermore, of the human gastric ESTs, 766 genes (9.5%) were present as putative alternatively spliced variants. Confirmation of the predicted spliced isoforms using RT-PCR showed that the predicted isoforms exist in gastric cancer cells and some isoforms coexist in gastric cell lines. These results provide potentially useful information for elucidating the molecular mechanisms associated with gastric oncogenesis.
Mammalian Genome – Springer Journals
Published: Dec 8, 2005
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.