Toxicity and Genotoxicity of Three Antimicrobials Commonly Used in Veterinary Medicine

Toxicity and Genotoxicity of Three Antimicrobials Commonly Used in Veterinary Medicine The toxicity of chlortetracycline (CTC), oxytetracycline (OTC) and enrofloxacin (ENF) was tested on two green algal species: the international standard Pseudokirchneriella subcapitata and the native Argentine species Ankistrodesmus fusiformis. All three antibiotics inhibited the algal growth. The most sensitive species was P. subcapitata, for which the EC50 for CTC, OTC and ENF were 1.19 ± 0.53, 0.92 ± 0.30 and 5.18 ± 3.80 mg L−1, respectively. The EC50 for A. fusiformis, were 3.23 ± 0.53, 7.15 ± 2.69 and 10.6 ± 1.28 mg L−1, respectively. The genotoxicity of these veterinary antibiotics was also assessed using chromosome aberration (CA) and micronuclei (MN) induction in Allium cepa roots. Three concentrations were tested (0.1, 1 and 10 mg L−1). Only ENF at 1 and 10 mg L−1 showed any significant MN induction. These data revealed that CTC, OTC and ENF could cause toxicity on green algae, whereas ENF could cause genotoxicity on A. cepa plants. Bulletin of Environmental Contamination and Toxicology Springer Journals

Toxicity and Genotoxicity of Three Antimicrobials Commonly Used in Veterinary Medicine

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Springer US
Copyright © 2017 by Springer Science+Business Media New York
Environment; Pollution, general; Environmental Health; Ecotoxicology; Soil Science & Conservation; Environmental Chemistry; Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution
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