To 90th Birthday of Georgii Viktorovich Lopashov

To 90th Birthday of Georgii Viktorovich Lopashov Russian Journal of Developmental Biology, Vol. 33, No. 5, 2002, pp. 322–323. Translated from Ontogenez, Vol. 33, No. 5, 2002, pp. 393–394. Original Russian Text Copyright © 2002 by Korochkin. JUBILEES After several preliminary studies (1935), Lopashov tried to follow a nascent molecular biology. This in view, he tried to answer the question whether the “killed” (by alcohol) eye rudiments were able to release substances that induced the eyes, rather than lenses. He answered this question positively (1936) but could not go further and isolate the inducing substances. These experiments served as a basis for studying the role of factors released by the eye cells in their own dif- ferentiation. It was shown that the pure pigment epithe- lium of tadpoles and adult frogs in the posterior cavity of their eyes, like in the retina clefts, transformed into retina (Lopashov, 1949; Lopashov and Sologub, 1972). However, this could be due to the stimulation of prolif- eration of the pigment epithelium cells. But it was shown in further experiments that the pigment epithe- lium covered by the lens epithelium differentiated into lentoids or retina with respect to whether these com- plexes were cultivated in a protein-free medium or transplanted at http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

To 90th Birthday of Georgii Viktorovich Lopashov

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Publisher
Springer Journals
Copyright
Copyright © 2002 by MAIK “Nauka/Interperiodica”
Subject
Life Sciences; Animal Anatomy / Morphology / Histology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1023/A:1020405326670
Publisher site
See Article on Publisher Site

Abstract

Russian Journal of Developmental Biology, Vol. 33, No. 5, 2002, pp. 322–323. Translated from Ontogenez, Vol. 33, No. 5, 2002, pp. 393–394. Original Russian Text Copyright © 2002 by Korochkin. JUBILEES After several preliminary studies (1935), Lopashov tried to follow a nascent molecular biology. This in view, he tried to answer the question whether the “killed” (by alcohol) eye rudiments were able to release substances that induced the eyes, rather than lenses. He answered this question positively (1936) but could not go further and isolate the inducing substances. These experiments served as a basis for studying the role of factors released by the eye cells in their own dif- ferentiation. It was shown that the pure pigment epithe- lium of tadpoles and adult frogs in the posterior cavity of their eyes, like in the retina clefts, transformed into retina (Lopashov, 1949; Lopashov and Sologub, 1972). However, this could be due to the stimulation of prolif- eration of the pigment epithelium cells. But it was shown in further experiments that the pigment epithe- lium covered by the lens epithelium differentiated into lentoids or retina with respect to whether these com- plexes were cultivated in a protein-free medium or transplanted at

Journal

Russian Journal of Developmental BiologySpringer Journals

Published: Oct 13, 2004

References

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