Eur J Orthop Surg Traumatol (2018) 28:457–461 https://doi.org/10.1007/s00590-017-2067-9 ORIGINAL ARTICLE • HIP - ARTHROPLASTY Tissue evacuated during joint replacement procedure as a source of mononuclear cells 2,3 2 2 2 Jakobsons Eriks · Erglis Kristaps · Patetko Liene · Erglis Martins · 2 2 2 1 Rasma Dortane · Beatrise Rupaine · Simona Krapse · Briede Ieva · 5 4 1,3 Valdis Goncars · Muiznieks Indrikis · Erglis Andrejs Received: 14 December 2016 / Accepted: 12 October 2017 / Published online: 1 November 2017 © The Author(s) 2017. This article is an open access publication Abstract Results Together, 34 bone marrow tissue processings were Background Different cell populations from bone mar - performed. On average, samples contained 46.31 ± 9.35 ml row were used in various clinical trials for cardiac diseases of bone marrow solution. Average cell yield in final prod - 6 6 during last decade. Four clinical studies are ongoing in our uct was 28.64 ± 9.35 × 10 MNCs and 0.77 ± 1.51 × 10 institution and enroll patients with cardiac diseases, coro- CD34+ population. In case of tissue removed during joint nary disease, type 2 diabetes, and osteoarthritis. The density replacement nine processings were performed. On aver- gradient is used to separate bone marrow mononuclear cells. age samples contained 450 ± 157.69 ml of tissue solution. Joint replacement procedures were associated with signifi
European Journal of Orthopaedic Surgery & Traumatology – Springer Journals
Published: Nov 1, 2017
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