Three-component synthesis of quinolone derivatives bearing 1,3-indandione moiety using pyridinium salts

Three-component synthesis of quinolone derivatives bearing 1,3-indandione moiety using pyridinium... A series of 3,4-disubstituted dihydroquinolin-2(1H)-ones have been synthesized via three-component reaction of 1,3-indandione with isatin derivatives and N-phenacyl pyridinium bromide salts in presence of triethylamine as basic reagent. This procedure affords a highly efficient route for accessing quinolones by ring expansion of isatin via a one-pot pathway. Products were obtained in good to moderate yield without requiring a chromatographic purification step. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Three-component synthesis of quinolone derivatives bearing 1,3-indandione moiety using pyridinium salts

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Publisher
Springer Netherlands
Copyright
Copyright © 2016 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-016-2808-0
Publisher site
See Article on Publisher Site

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