Thinking about RNA? MicroRNAs in the brain

Thinking about RNA? MicroRNAs in the brain MicroRNAs (miRNAs) are a recently discovered class of small RNA molecules implicated in a wide range of diverse gene regulatory mechanisms. Interestingly, numerous miRNAs are expressed in a spatially and temporally controlled manner in the nervous system. This suggests that gene regulation networks based on miRNA activities may be particularly relevant in neurons. Recent studies show the involvement of RNA-mediated gene silencing in neurogenesis, neural differentiation, synaptic plasticity, and neurologic and psychiatric diseases. This review focuses on the roles of miRNAs in the gene regulation of the nervous system. Mammalian Genome Springer Journals

Thinking about RNA? MicroRNAs in the brain

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Copyright © 2008 by Springer Science+Business Media, LLC
Life Sciences; Zoology ; Anatomy ; Cell Biology
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