Thiazolyl-pyrazole-biscoumarin synthesis and evaluation of their antibacterial and antioxidant activities

Thiazolyl-pyrazole-biscoumarin synthesis and evaluation of their antibacterial and antioxidant... + 1 R 1 6 + + Ar 2 2 Ar' 2 2 2 2 Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2644-2) contains supplementary material, which is available to authorized users. & Nosrat O. Mahmoodi; Department of Organic Chemistry, Faculty of Sciences, University of Guilan, PO Box 41335-1914, Rasht, Iran Faculty of Science, School of Chemistry, University of Tehran, Tehran, Iran %U 1+ 662 N. O. Mahmoodi, S. Ghodsi Keywords Thiazolo-pyrazolium  Coumarin  One-pot reaction  Antibacterial Antioxidant Introduction In recent years, many studies, either by our research group or others, were carried out on heterocyclic systems bearing thiazole and pyrazoline groups as pharma- cophores. Compounds possessing pyrazoles and pyrazolines are an interesting class of heterocycles because of their synthetic flexibility and useful biological activities [1], serving as antimicrobials [2, 3], antivirals [4], anti-inflammatories [5, 6], antidepressants [7], antituberculars [8], antiamoebics [9], and analgesics [10]. Similarly, the thiazole moiety is a prevalent scaffold in a number of naturally occurring and synthetic molecules with remarkable medicinal value due to their potential chemotherapeutic [11], fungicidal [12], antiviral [13], antibacterial [14], anti-HIV [15], hypnotic [16], pesticidal [17], anticonvulsant, anti-inflammatory [18] enzyme inhibition [19] and antitumour activities Research on Chemical Intermediates Springer Journals

Thiazolyl-pyrazole-biscoumarin synthesis and evaluation of their antibacterial and antioxidant activities

Loading next page...
Springer Netherlands
Copyright © 2016 by Springer Science+Business Media Dordrecht
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial