+ 1 R 1 6 + + Ar 2 2 Ar' 2 2 2 2 Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2644-2) contains supplementary material, which is available to authorized users. & Nosrat O. Mahmoodi email@example.com; firstname.lastname@example.org Department of Organic Chemistry, Faculty of Sciences, University of Guilan, PO Box 41335-1914, Rasht, Iran Faculty of Science, School of Chemistry, University of Tehran, Tehran, Iran %U 1+ 662 N. O. Mahmoodi, S. Ghodsi Keywords Thiazolo-pyrazolium Coumarin One-pot reaction Antibacterial Antioxidant Introduction In recent years, many studies, either by our research group or others, were carried out on heterocyclic systems bearing thiazole and pyrazoline groups as pharma- cophores. Compounds possessing pyrazoles and pyrazolines are an interesting class of heterocycles because of their synthetic ﬂexibility and useful biological activities , serving as antimicrobials [2, 3], antivirals , anti-inﬂammatories [5, 6], antidepressants , antituberculars , antiamoebics , and analgesics . Similarly, the thiazole moiety is a prevalent scaffold in a number of naturally occurring and synthetic molecules with remarkable medicinal value due to their potential chemotherapeutic , fungicidal , antiviral , antibacterial , anti-HIV , hypnotic , pesticidal , anticonvulsant, anti-inﬂammatory  enzyme inhibition  and antitumour activities
Research on Chemical Intermediates – Springer Journals
Published: Jul 13, 2016
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