ISSN 1070-4272, Russian Journal of Applied Chemistry, 2006, Vol. 79, No. 10, pp. 1705!1708. C Pleiades Publishing, Inc., 2006.
Original Russian Text C A.V. Boldashevskii, Zh.K. Tukhmetova, Sh.B. Kasenova, S.M. Adekenov, A. Nukhuly, B.K. Kasenov, A.M. Gazaliev, S.D. Fazylov,
2006, published in Zhurnal Prikladnoi Khimii, 2006, Vol. 79, No. 10, pp. 1725!1727.
Thermochemistry of Potassium Morpholinodithiocarbamate
A. V. Boldashevskii, Zh. K. Tukhmetova, Sh. B. Kasenova, S. M. Adekenov,
A. Nukhuly, B. K. Kasenov, A. M. Gazaliev, and S. D. Fazylov
Institute of Phytochemistry, Karaganda, Republic of Kazakhstan
Institute of Organic Synthesis and Coal Chemistry, Karaganda, Republic of Kazakhstan
Pavlodar University, Pavlodar, Republic of Kazakhstan
Received March 24, 2006
Abstract-Results of thermochemical studies of a new compound, potassium morpholinodithiocarbamate, are
presented. The enthalpies of its solution in water at various dilutions and the specific heat at 1733348 K were
examined by the experimental methods of isothermal and dynamic calorimetry.
Bioactive substances forming the basis of medici-
nals are of particular importance for the human life.
To compounds of this kind also belong morpholine
derivatives, which occupy a prominent place among
the known analgesics, antiarrythmatics, antidepres-
sants, etc. .
Studies of the thermodynamic properties of bio-
active substances and their derivatives are of high
theoretical and practical importance for their directed
synthesis and for revealing the relationship between
their structural and energy-related characteristics.
In this context, we performed a calorimetric study
to determine the enthalpies of solution in water of
a new compound, potassium morpholinodithiocarba-
mate, and its specific heat in the temperature range
The sample under study was potassium morpho-
of chemically pure grade,
= 230oC, empirical formula C
molecular weight 201.3434. The structural formula of
the compound is as follows:
Synthesized at the Institute of Organic Synthesis and Coal
Chemistry, Karaganda, Republic of Kazakhstan.
The enthalpy of solution of this compound was
studied on a DAK-I-IA automated differential calo-
rimeter under isothermal conditions (25oC) at various
dilutions (1 : 18 000, 1 : 36 000, and 1 : 72 000 moles
of compound per moles of water). The theory and
practice of calorimetric studies was described in de-
tail in . The technical parameters of the calo-
rimeter are as follows: working temperature range
253200oC, ampule volume 8 cm
, sensitivity in
the mode of a direct measurement of the thermal elec-
tromotive force not worse than 0.012 mV, error in
measurement of heat effects not exceeding 2.0%. Heat
effects were recorded with a KSP-4 potentiometer,
and also using an IP-4 precision integrator. The time
of preliminary thermostating was 2 h. The substance
under study was placed in a metallic ampule, which
was inserted into a metallic cartridge with the sol-
The operation of the device was checked by meas-
uring the enthalpy of solution of thrice recrystallized
KCl at dilutions of 1 : 1600, 1 : 2400, and 1 : 3200
(moles of salt per moles of water). The value obtained
at 25oC, DH
= 17 780 + 262 J mol
, is in a good
agreement with the reference values reported in
The experimental errors and the homogeneities of
their variances were calculated using the Student and
Cochran criteria .
The significance level of the criteria employed was
5%. The regression line had the following parameters: