Therapeutic radiation for lymphoma and risk of second primary malignant mesothelioma

Therapeutic radiation for lymphoma and risk of second primary malignant mesothelioma Cancer Causes Control (2017) 28:971–979 DOI 10.1007/s10552-017-0929-4 BRIEF REPORT Therapeutic radiation for lymphoma and risk of second primary malignant mesothelioma 1,2 1 1 3 • • • Ellen T. Chang Edmund C. Lau Fionna S. Mowat M. Jane Teta Received: 12 January 2017 / Accepted: 20 July 2017 / Published online: 28 July 2017 Springer International Publishing AG 2017 Abstract Conclusions The increase in second primary mesothelioma Purpose This large, population-based U.S. study of lym- risk following radiotherapy for lymphoma is independent phoma patients followed for up to four decades enables of several patient and disease characteristics, and is higher detailed analysis of second primary mesothelioma risk after with earlier treatment era and longer latency. radiotherapy. Methods U.S. Surveillance, Epidemiology, and End Keywords Hodgkin lymphoma  Non-Hodgkin Results data were used to identify second primary lymphoma  Mesothelioma  Radiotherapy  Epidemiology mesothelioma among patients diagnosed with Hodgkin SEER Program lymphoma (HL) or non-Hodgkin lymphoma (NHL) between 1973 and 2014. Standardized incidence ratios (SIRs) were calculated by radiotherapy. Multivariate Introduction adjusted associations were examined using competing risks survival analysis. Ionizing radiation, a known human carcinogen, has been Results Among 47,219 HL patients (19,538 irradiated) and used since the 1950s Cancer Causes & Control Springer Journals

Therapeutic radiation for lymphoma and risk of second primary malignant mesothelioma

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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG
Biomedicine; Cancer Research; Biomedicine, general; Oncology; Public Health; Epidemiology; Hematology
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