Leitthema 1,2 2 Z Epileptol Vincent Alvarez ·AndreaO.Rossetti https://doi.org/10.1007/s10309-018-0194-x Hôpital de Sion, Sion, Switzerland Département des Neurosciences Cliniques, Centre Hospitalier Universitare Vaudois et Faculté de Biologie © Springer Medizin Verlag GmbH, ein Teil von et Médecine, Université de Lausanne, Lausanne, Switzerland Springer Nature 2018 Therapeutic coma for the treatment of status epilepticus Timing, choice of drug, and impact on prognosis impairment) may show a higher mag- Introduction When is pharmacological coma nitude of eﬀect ; this aspect had indicated? Status epilepticus (SE) represents, aer ft already been suggested, albeit with non- stroke, the most frequent neurological A clinician facing refractory SE has two signiﬁcant results . Furthermore, emergency with potential impact on sur- basic options: to pursue treatment with the Lausanne study highlighted higher vival, and involves a tight team work of nonsedating anticonvulsants, or to intu- infection rates in intubated patients . neurologists, clinical neurophysiologists, bate the patient and induce pharmaco- A recent analysis of two retrospective co- emergency physicians, and (neuro-)in- logical coma. Important concerns about horts in Basel and Baltimore conﬁrmed tensivists. The use of a structured al- irreversible brain damage resulting from that use of anesthetics is independently gorithm including subsequent treatment ongoingseizureactivity, whicharemostly associated
Zeitschrift für Epileptologie – Springer Journals
Published: May 30, 2018
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