Mammalian Genome 11, 164–168 (2000). Incorporating Mouse Genome © Springer-Verlag New York Inc. 2000 The ubiquitin-activating enzyme E1 homologous genes on the mouse Y Chromosome (Ube1y) represent one functional gene and six partial pseudogenes 1,2 1,2 3 1 Nicolas Le ´vy, Andre ´ Navarro, Colin E. Bishop, Michael J. Mitchell INSERM U491: “Ge ´ne ´tique Me ´dicale et De ´veloppement”, Faculte´de Me ´decine de la Timone, 27, Boulevard Jean Moulin, 13385 Marseille CEDEX 5, France Laboratoire de Ge ´ne ´tique Mole ´culaire, Ho ˆ pital de la Timone, Marseille, France Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA Received: 18 June 1999 / Accepted: 13 September 1999 b b The Sxr deletion interval (DSxr ) of the mouse Y Chromosome ture of the Ube1y gene on the mouse Y Chr. In addition, we have (Chr) encodes the spermatogenesis factor, Spy, which is required fine-mapped Ube1y-related sequences present on the mouse Y Chr for the normal proliferation of mitotic germ cells (Sutcliffe and and confirm that the only complete transcription unit is the Ube1y Burgoyne 1989). The molecular characterization of DSxr has re- gene located within the DSxr interval. vealed that it is rich in genes
Mammalian Genome – Springer Journals
Published: Feb 1, 2000
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