Clin Transl Oncol (2017) 19:1141–1146 DOI 10.1007/s12094-017-1651-0 RESEARCH AR TIC L E The TNM 8 M1b and M1c classiﬁcation for non-small cell lung cancer in a cohort of patients with brain metastases 1,2 3 3,4 3,4 3,4 • • • • C. Nieder M. Hintz O. Oehlke A. Bilger A. L. Grosu Received: 14 February 2017 / Accepted: 18 March 2017 / Published online: 29 March 2017 Federacio ´ n de Sociedades Espan ˜ olas de Oncologı ´a (FESEO) 2017 Abstract Conclusions We found the M1b classiﬁcation to provide Background and purpose According to the recent TNM 8 clinically relevant information. The multivariate analysis classiﬁcation, patients with metastatic non-small cell lung suggested that patients with M1b disease, better perfor- cancer (NSCLC) and single extrathoracic metastasis should mance status and younger age have better survival. be classiﬁed as stage M1b, while those with 2 or more metastases comprise stage M1c. The purpose of this study Keywords Brain metastases Lung cancer was to analyze the impact of this classiﬁcation in patients Radiotherapy Prognostic factors with brain metastases. Materials and methods This retrospective study included 172 patients treated with individualized approaches. Introduction Actuarial survival was calculated. Uni- and multivariate analyses
Clinical and Translational Oncology – Springer Journals
Published: Mar 29, 2017
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