Mammalian Genome 8, 689-691 (1997). jtjlr aA/2LL/_ n h ur/ e//o///e 9 Spnnger-Verlag New York Inc. 1997 The structure of DXF34, a human X-linked sequence family with homology to a transcribed mouse Y-linked repeat S.H. Laval, V. Reed, H.J. Blair, Y. Boyd Molecular Genetics Group, MRC Mammalian Genetics Unit, Harwell, Oxon OX11 ORD, UK Received: 20 January 1997 / Accepted: 10 April 1997 mouse X Chr (Disteche et al. 1987). It may be concluded that the The most intensively studied mammalian genome other than the mouse sequence family equivalent to DXF34, DXHXF34, lies human is that of the mouse. Comparative studies of the human close to DXWas70 on the mouse X Chr and, since no single YAC and mouse genomes may indicate those sequences that have been clone contained all of the major restriction fragments, this family conserved during the evolution of mammalian orders and hence are likely to be of biological significance. One experiment based must be localized within the 1.2 Mb covered by two of the smallest upon this approach, the isolation and mapping of conserved hy- overlapping YAC clones. This is consistent with the finding that bridization probes, has produced data on the manner in which
Mammalian Genome – Springer Journals
Published: Mar 31, 2009
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