Mammalian Genome 10, 750–752 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 The spontaneous coat color mutant white nose (wn) maps to murine Chromosome 15 1 2 2 3 3 Peter W. Marks, Jennifer L. Bandura, Dar-Bin Shieh, Dorothee Foernzler, David R. Beier, David J. Kwiatkowski Department of Adult Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA Received: 22 December 1998 / Accepted 26 February 1999 Fancy mice, having variation in coat color, were the progenitors of In order to map the wn locus in a backcross panel (Silver the earliest laboratory mice. These animals were readily amenable 1995), we utilized the C3H/HeJ strain (obtained from The Jackson to genetic study because of their observable phenotypes. About 80 Laboratory, Bar Harbor, Me.) after initial attempts using M. m. classical mutations affecting mouse coat color have been described castaneus were unsuccessful. The C3H/HeJ strain was chosen, to date. A number of the genes in which these mutations occur among others, because
Mammalian Genome – Springer Journals
Published: Jul 1, 1999
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