The role of whole-lesion apparent diffusion coefficient analysis for predicting outcomes of prostate cancer patients on active surveillance

The role of whole-lesion apparent diffusion coefficient analysis for predicting outcomes of... follow-up biopsy compared with 3.6% ± 64.6% in Purpose: To explore the role of whole-lesion apparent remaining patients (P = 0.050). diffusion coefficient (ADC) analysis for predicting out- Conclusion: Our preliminary results suggest a role for 3D comes in prostate cancer patients on active surveillance. whole-lesion ADC analysis in prostate cancer active Methods: This study included 72 prostate cancer patients surveillance. who underwent MRI–ultrasound fusion-targeted biopsy at the initiation of active surveillance, had a visible MRI Key words: Prostate cancer—Active surveillance— lesion in the region of tumor on biopsy, and underwent DWI—MRI—Apparent diffusion coefficient 3T baseline and follow-up MRI examinations separated by at least one year. Thirty of the patients also underwent an additional MRI–ultrasound fusion-tar- Active surveillance (AS) is a management approach for geted biopsy after the follow-up MRI. Whole-lesion men with low-risk localized prostate cancer seeking to ADC metrics and lesion volumes were computed from avoid the side effects of radical therapy while preserving 3D whole-lesion volumes-of-interest placed on lesions on the opportunity for curative intervention [1–3]. Although the baseline and follow-up ADC maps. The percent follow-up in AS is usually performed by serial PSA change in lesion volume on the ADC map between the measurement, digital http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Abdominal Radiology Springer Journals

The role of whole-lesion apparent diffusion coefficient analysis for predicting outcomes of prostate cancer patients on active surveillance

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media New York
Subject
Medicine & Public Health; Imaging / Radiology; Gastroenterology; Hepatology
ISSN
2366-004X
eISSN
2366-0058
D.O.I.
10.1007/s00261-017-1135-2
Publisher site
See Article on Publisher Site

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