The role of hepatic enzymes in Crohn’s disease

The role of hepatic enzymes in Crohn’s disease Int J Colorectal Dis (2017) 32:1363–1364 DOI 10.1007/s00384-017-2829-1 LETTER TO THE EDITOR 1 1 2 Davide Giuseppe Ribaldone & Marco Astegiano & Rinaldo Pellicano Accepted: 27 April 2017 /Published online: 4 May 2017 Springer-Verlag Berlin Heidelberg 2017 Dear Editor: A recent interesting retrospective study was performed in A systematic review has reported that, in Crohn’sdis- 383 newly diagnosed (not treated) CD patients. One patient ease (CD) patients, the prevalence of cholelithiasis ranged with chronic liver disease (small-duct PSC) was excluded. Of from 11 to 34%, that of primary sclerosing cholangitis the 383 patients included in this study, 131 had liver test ab- normalities (34.1%), but liver diseases were not found, apart (PSC) from 1.2 to 3.4%, that of fatty liver disease 23%, and hepatic amyloidosis occurred in <1% [1]. In a prospec- from liver steatosis in 6% of patients [3](versus 29%in the tive, single-blind study, we evaluated the prevalence of previous study [2]). histological changes in the liver of patients with CD, with- The two studies [2, 3] agree that, considering the out alterations of both liver biochemical tests and ultra- cost/benefit ratio, patients with CD should be considered as sound, and their prognostic significance. The patients healthy from International Journal of Colorectal Disease Springer Journals

The role of hepatic enzymes in Crohn’s disease

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Springer Berlin Heidelberg
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Medicine & Public Health; Surgery; Internal Medicine; Gastroenterology; Hepatology; Proctology
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