The role of hepatic enzymes in Crohn’s disease

The role of hepatic enzymes in Crohn’s disease Int J Colorectal Dis (2017) 32:1363–1364 DOI 10.1007/s00384-017-2829-1 LETTER TO THE EDITOR 1 1 2 Davide Giuseppe Ribaldone & Marco Astegiano & Rinaldo Pellicano Accepted: 27 April 2017 /Published online: 4 May 2017 Springer-Verlag Berlin Heidelberg 2017 Dear Editor: A recent interesting retrospective study was performed in A systematic review has reported that, in Crohn’sdis- 383 newly diagnosed (not treated) CD patients. One patient ease (CD) patients, the prevalence of cholelithiasis ranged with chronic liver disease (small-duct PSC) was excluded. Of from 11 to 34%, that of primary sclerosing cholangitis the 383 patients included in this study, 131 had liver test ab- normalities (34.1%), but liver diseases were not found, apart (PSC) from 1.2 to 3.4%, that of fatty liver disease 23%, and hepatic amyloidosis occurred in <1% [1]. In a prospec- from liver steatosis in 6% of patients [3](versus 29%in the tive, single-blind study, we evaluated the prevalence of previous study [2]). histological changes in the liver of patients with CD, with- The two studies [2, 3] agree that, considering the out alterations of both liver biochemical tests and ultra- cost/benefit ratio, patients with CD should be considered as sound, and their prognostic significance. The patients healthy from http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Colorectal Disease Springer Journals

The role of hepatic enzymes in Crohn’s disease

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Surgery; Internal Medicine; Gastroenterology; Hepatology; Proctology
ISSN
0179-1958
eISSN
1432-1262
D.O.I.
10.1007/s00384-017-2829-1
Publisher site
See Article on Publisher Site

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