Eur J Nucl Med Mol Imaging (2017) 44:1712–1720 DOI 10.1007/s00259-017-3698-0 ORIGINAL ARTICLE The role of F-FDG PET/CT in the detection of osteosarcoma recurrence 1 2 2 2 Andrea Angelini & Francesco Ceci & Paolo Castellucci & Tiziano Graziani & 2 1 3 3 Giulia Polverari & Giulia Trovarelli & Emanuela Palmerini & Stefano Ferrari & 2 1 Stefano Fanti & Pietro Ruggieri Received: 12 January 2017 /Accepted: 28 March 2017 /Published online: 12 April 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract in 2.7% (1/37) case; multiple sites of uptake in 32.4% (12/37). Aim The aim of this study was to investigate the diagnostic Histology resulted positive in 92% (34/37) of patients. A total accuracy of F-FDG-PET/CT in osteosarcoma patients sus- of 51 pathologic lesions were evaluated (22 local relapse, 11 picious for disease recurrence after adequate surgical therapy. lung metastasis, 10 metastatic LNs, eight distant metastatic Methods Inclusion criteria were: a) adequate surgical treatment lesions). On a per-patient analysis F-FDG-PET/CT showed for proven osteosarcoma and documented complete remission a sensitivity, specificity, accuracy, PPV, and NPV of 91%, after therapy; b) F-FDG-PET/CT performed during follow- 75%, 89%, 97%, 50%. On a per-site analysis the performance up for clinical/diagnostic suspicion of relapse;
European Journal of Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Apr 12, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera