Transl. Stroke Res. (2018) 9:199–200 DOI 10.1007/s12975-017-0573-z EDITORIAL The Protein Modification and Degradation Pathways after Brain Ischemia 1,2 1,2 Tibor Kristian & Bingren Hu Received: 19 September 2017 /Accepted: 21 September 2017 /Published online: 1 October 2017 Springer Science+Business Media, LLC 2017 This Special Issue of Translational Stroke Research is focused of cellular metabolic pathways, some may have a more sig- on the protein modification and degradation pathways after nificant impact on cell fate than others. To survive this patho- brain ischemia and is a continuation of a previous special issue logic environment, post-ischemic neurons must cope with re- in this journal entitled: BThe protein degradation pathways pair and eliminate irreversibly damaged organelles and toxic materials by upregulation of cellular defense systems. after brain ischemia^ . Articles in this current issue sum- marize recent developments and understanding of protein ag- This special issue of Translational Stroke Research is fo- gregation, modification, and degradation triggered by ische- cused on alterations in protein metabolism, degradation mech- mic insult. This Special Issue seeks to reiterate that disruption anisms, and post-translational modifications following brain in cellular protein metabolism remains an important aspect of ischemic insult. Each individual article highlights and dis- ischemic brain
Translational Stroke Research – Springer Journals
Published: Oct 1, 2017
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