Int Urol Nephrol (2017) 49:1577–1583 DOI 10.1007/s11255-017-1648-1 UROLOGY - ORIGINAL PAPER The prognostic significance of preoperatively assessed AST/ ALT (De Ritis) ratio on survival in patients underwent radical cystectomy 1 1 2 3 1 Sacit Nuri Gorgel · Osman Kose · Esra Meltem Koc · Erhan Ates · Yigit Akin · Yuksel Yilmaz Received: 3 June 2017 / Accepted: 29 June 2017 / Published online: 1 July 2017 © Springer Science+Business Media B.V. 2017 Abstract T stage (HR 5.42, 95% CI 2.63–11.64; p < 0.001) and age Purposes We aimed to evaluate prognostic significance (HR 1.05, 95% CI 1.02–1.08; p = 0.001) were determined of preoperatively assessed aspartate aminotransaminase as independent prognostic factors. (AST)/alanine aminotransferase (ALT) (De Ritis) ratio on Conclusions Preoperative elevated De Ritis ratio could be survival in bladder cancer (BC) patients underwent radical an independent prognostic factor in BC patients underwent cystectomy (RC). RC. Our results should be confirmed by large and properly Methods We, respectively, analysed clinical and pathologi- designed prospective, randomized trials. cal data of 153 patients who underwent RC for BC between February 2006 and December 2016 at a tertiary level hos- Keywords Aminotransferases · Bladder cancer · Radical pital. The potential prognostic
International Urology and Nephrology – Springer Journals
Published: Jul 1, 2017
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