Ann Surg Oncol (2017) 24:2438–2446 DOI 10.1245/s10434-017-5904-5 O R I G IN AL ARTI CL E – HE PA TOBILI ARY T U M O R S The Prognostic Impact of Determining Resection Margin Status for Multiple Colorectal Metastases According to the Margin of the Largest Lesion 1 1 1 1 Kazunari Sasaki, MD , Georgios A. Margonis, MD, PhD , Kosuke Maitani, MD , Nikolaos Andreatos, MD , 1 2 1 1 Jaeyun Wang, BSc , Emmanouil Pikoulis, MD , Jin He, MD, PhD , Christopher L. Wolfgang, MD, PhD , 1 1 Matthew Weiss, MD , and Timothy M. Pawlik, MD, MPH, PhD Division of Surgical Oncology, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; First Department of Surgery, Laiko Hospital, University of Athens, Athens, Greece ABSTRACT (P = 0.009). On multivariate analysis, although the prog- Background. Although the prognostic role of surgical nostic impact of all R1 was not associated with OS (hazard margin status after resection of colorectal liver metastasis ratio [HR] 1.56; P = 0.08), R1-Type 2 margin status (CRLM) has been previously examined, controversy still independently predicted a poor outcome (HR 1.93; surrounds the importance of surgical margin status in
Annals of Surgical Oncology – Springer Journals
Published: Jul 10, 2017
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