The prognostic effect of estrogen receptor status differs for younger versus older breast cancer patients

The prognostic effect of estrogen receptor status differs for younger versus older breast cancer... Breast Cancer Res Treat (2017) 165:391–402 DOI 10.1007/s10549-017-4333-2 EPIDEMIOLOGY The prognostic effect of estrogen receptor status differs for younger versus older breast cancer patients 1 1 1 • • Victoria Sopik Ping Sun Steven A. Narod Received: 17 April 2017 / Accepted: 7 June 2017 / Published online: 10 June 2017 Springer Science+Business Media, LLC 2017 Abstract diagnosed before age 40, breast cancer-specific survival at Purpose To estimate the prognostic impact of estrogen 15 years was worse for those with ER-positive breast receptor (ER)-status among women with primary invasive cancer than for those with ER-negative breast cancer (55 breast cancer, according to age at diagnosis. vs. 61%; adjusted HR = 0.90; 95% CI 0.57–1.41; Methods We studied 1910 women with primary invasive p = 0.64). In contrast, among 1697 women diagnosed breast cancer (stages I–III) who were treated at Women’s between ages 40 and 75, breast cancer-specific survival at College Hospital between 1987 and 2000. For each patient, 15 years was better for those with ER-positive breast we obtained information on age at diagnosis, tumour size, cancer than for those with ER-negative breast cancer (78 lymph node status, ER-status, treatments received (radio- vs. 72%; adjusted HR = 0.60; 95% http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Breast Cancer Research and Treatment Springer Journals

The prognostic effect of estrogen receptor status differs for younger versus older breast cancer patients

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Oncology
ISSN
0167-6806
eISSN
1573-7217
D.O.I.
10.1007/s10549-017-4333-2
Publisher site
See Article on Publisher Site

Abstract

Breast Cancer Res Treat (2017) 165:391–402 DOI 10.1007/s10549-017-4333-2 EPIDEMIOLOGY The prognostic effect of estrogen receptor status differs for younger versus older breast cancer patients 1 1 1 • • Victoria Sopik Ping Sun Steven A. Narod Received: 17 April 2017 / Accepted: 7 June 2017 / Published online: 10 June 2017 Springer Science+Business Media, LLC 2017 Abstract diagnosed before age 40, breast cancer-specific survival at Purpose To estimate the prognostic impact of estrogen 15 years was worse for those with ER-positive breast receptor (ER)-status among women with primary invasive cancer than for those with ER-negative breast cancer (55 breast cancer, according to age at diagnosis. vs. 61%; adjusted HR = 0.90; 95% CI 0.57–1.41; Methods We studied 1910 women with primary invasive p = 0.64). In contrast, among 1697 women diagnosed breast cancer (stages I–III) who were treated at Women’s between ages 40 and 75, breast cancer-specific survival at College Hospital between 1987 and 2000. For each patient, 15 years was better for those with ER-positive breast we obtained information on age at diagnosis, tumour size, cancer than for those with ER-negative breast cancer (78 lymph node status, ER-status, treatments received (radio- vs. 72%; adjusted HR = 0.60; 95%

Journal

Breast Cancer Research and TreatmentSpringer Journals

Published: Jun 10, 2017

References

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