Ann Surg Oncol (2018) 25:2612–2619 https://doi.org/10.1245/s10434-018-6519-1 OR IG INA L A R TIC L E – BREA S T O NC OLOG Y The Potential Impact of AMAROS on the Management of the Axilla in Patients with Clinical T1-2N0 Breast Cancer Undergoing Primary Total Mastectomy 1 2,3 4 4 5 Martine Moossdorff, MD , Faina Nakhlis, MD , Jiani Hu, MPH , William T. Barry, PhD , Katya Losk, MPH , 2 1 2,3 Courtney Haskett , Marjolein L. Smidt, MD, PhD , and Tari A. King, MD Department of Surgery, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, 2 3 Maastricht, The Netherlands; Department of Surgery, Brigham and Women’s Hospital, Boston, MA; Dana-Farber/ Brigham and Women’s Cancer Center, Boston, MA; Department of Biostatistics and Computational Biology, Dana- Farber Cancer Institute, Boston, MA; Medical Oncology, Dana-Farber Cancer Institute, Boston, MA ABSTRACT nodes. In the multivariate analysis, age younger than Background. Recent trials have demonstrated that axil- 50 years (odds ratio [OR] 3.55; 95% conﬁdence interval lary observation or axillary radiation therapy (AxRT) is [CI] 1.57–8.45), lymphovascular invasion (LVI) (OR equivalent to axillary node dissection (ALND) for patients 5.78; 95% CI 2.53–4.78), macrometastases (OR 3.99; with one
Annals of Surgical Oncology – Springer Journals
Published: May 31, 2018
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