Cancer Causes Control (2017) 28:959–969 DOI 10.1007/s10552-017-0933-8 OR IGINAL PAPER The oral microbiota in patients with pancreatic cancer, patients with IPMNs, and controls: a pilot study 1 1 2 3 4 • • • • • Sara H. Olson Jaya Satagopan Youming Xu Lilan Ling Siok Leong 4 1 5 1 1 • • • • • Irene Orlow Amethyst Saldia Peter Li Pamela Nunes Vincent Madonia 6 7 3 8 • • • Peter J. Allen Eileen O’Reilly Eric Pamer Robert C. Kurtz Received: 18 January 2017 / Accepted: 21 July 2017 / Published online: 31 July 2017 Springer International Publishing AG 2017 Abstract bacterial species were comprehensively surveyed by Purpose Poor oral health appears to be a risk factor for sequencing of the 16S rRNA microbial genes. We obtained pancreatic cancer, possibly implicating the oral microbiota. measures of diversity and the mean relative proportions of In this pilot study, we evaluated the characteristics of the individual taxa. We explored the degree to which these oral microbiota in patients with pancreatic ductal adeno- measures differed according to respondent characteristics carcinoma (PDAC), intraductal papillary mucinous neo- based on individual interviews. plasms (IPMN), and healthy controls. Results PDAC cases did
Cancer Causes & Control – Springer Journals
Published: Jul 31, 2017
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