The Negative Survival Impact of Infectious Complications After Surgery is Canceled Out by the Response of Neoadjuvant Chemotherapy in Patients with Esophageal Cancer

The Negative Survival Impact of Infectious Complications After Surgery is Canceled Out by the... Ann Surg Oncol (2018) 25:2034–2043 https://doi.org/10.1245/s10434-018-6504-8 O R I G IN AL ARTI CL E – GA STROIN TESTINA L O N C OLO G Y The Negative Survival Impact of Infectious Complications After Surgery is Canceled Out by the Response of Neoadjuvant Chemotherapy in Patients with Esophageal Cancer 1 2 1 2 Kazuki Kano, MD , Toru Aoyama, MD, PhD , Takaki Yoshikawa, MD, PhD , Yukio Maezawa, MD , 1 1 1 2 Tetsushi Nakajima, MD , Tsutomu Hayashi, MD , Takanobu Yamada, MD, PhD , Tsutomu Sato, MD, PhD , 2 2 2 1 Takashi Oshima, MD, PhD , Yasushi Rino, MD, PhD , Munetaka Masuda, MD, PhD , Haruhiko Cho, MD, PhD , and Takashi Ogata, MD, PhD 1 2 Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan; Department of Surgery, Yokohama City University, Yokohama, Japan ABSTRACT interval [CI] 1.057–5.263, p = 0.036). In the subset anal- Background. This study was designed to investigate ysis, postoperative ICs were a marginally significant whether postoperative infectious complications (ICs) are a independent risk factor for OS in the nonresponders (HR risk factor for the prognosis in esophageal cancer patients 2.862; 95% CI 0.942–8.696, p = 0.063) but http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Surgical Oncology Springer Journals

The Negative Survival Impact of Infectious Complications After Surgery is Canceled Out by the Response of Neoadjuvant Chemotherapy in Patients with Esophageal Cancer

Download PDF
10 pages
Read Article

Loading next page...
 
/lp/springer_journal/the-negative-survival-impact-of-infectious-complications-after-surgery-WusSvecIL3
Publisher
Springer Journals
Copyright
Copyright © 2018 by Society of Surgical Oncology
Subject
Medicine & Public Health; Surgical Oncology; Oncology; Surgery
ISSN
1068-9265
eISSN
1534-4681
DOI
10.1245/s10434-018-6504-8
Publisher site
See Article on Publisher Site

Abstract

Ann Surg Oncol (2018) 25:2034–2043 https://doi.org/10.1245/s10434-018-6504-8 O R I G IN AL ARTI CL E – GA STROIN TESTINA L O N C OLO G Y The Negative Survival Impact of Infectious Complications After Surgery is Canceled Out by the Response of Neoadjuvant Chemotherapy in Patients with Esophageal Cancer 1 2 1 2 Kazuki Kano, MD , Toru Aoyama, MD, PhD , Takaki Yoshikawa, MD, PhD , Yukio Maezawa, MD , 1 1 1 2 Tetsushi Nakajima, MD , Tsutomu Hayashi, MD , Takanobu Yamada, MD, PhD , Tsutomu Sato, MD, PhD , 2 2 2 1 Takashi Oshima, MD, PhD , Yasushi Rino, MD, PhD , Munetaka Masuda, MD, PhD , Haruhiko Cho, MD, PhD , and Takashi Ogata, MD, PhD 1 2 Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan; Department of Surgery, Yokohama City University, Yokohama, Japan ABSTRACT interval [CI] 1.057–5.263, p = 0.036). In the subset anal- Background. This study was designed to investigate ysis, postoperative ICs were a marginally significant whether postoperative infectious complications (ICs) are a independent risk factor for OS in the nonresponders (HR risk factor for the prognosis in esophageal cancer patients 2.862; 95% CI 0.942–8.696, p = 0.063) but

Journal

Annals of Surgical Oncology – Springer Journals

Published: May 10, 2018

References

  • Global cancer statistics
    Jemal, A; Bray, F; Center, MM
  • Medical Research Council Oesophageal Cancer Working G. Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomized controlled trial
    Bancewicz, J; Clark, PI; Smith, DB
  • Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer
    Kelsen, DP; Winter, KA; Gunderson, LL
  • A randomized trial comparing postoperative adjuvant chemotherapy with cisplatin and 5-fluorouracil versus preoperative chemotherapy for localized advanced squamous cell carcinoma of the thoracic esophagus (JCOG9907)
    Ando, N; Kato, H; Igaki, H
  • Chemoradiotherapy followed by surgery compared with surgery alone in squamous cell cancer of the esophagus
    Bosset, JF; Gignoux, M; Triboulet, JP
  • Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial
    Burmeister, BH; Smithers, BM; Gebski, V
  • Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781
    Tepper, J; Krasna, MJ; Niedzwiecki, D
  • Preoperative chemoradiotherapy for esophageal or junctional cancer
    Hagen, P; Hulshof, MC; Lanschot, JJ
  • Preoperative chemotherapy for clinically node-positive patients with squamous cell carcinoma of the esophagus
    Yano, M; Tachi, Y; Doki, Y
  • Oesophageal carcinoma
    Pennathur, A; Gibson, MK; Jobe, BA
  • Prognostic impact of postoperative morbidity after esophagectomy for esophageal cancer
    Kataoka, K; Takeuchi, H; Mizusawa, J
  • Postoperative infectious complications are associated with adverse oncologic outcomes in esophageal cancer patients undergoing preoperative chemotherapy
    Yamashita, K; Makino, T; Miyata, H
  • Determinants of long-term survival after major surgery and the adverse effect of postoperative complications
    Khuri, SF; Henderson, WG; DePalma, RG
  • Postoperative complications after esophagectomy for adenocarcinoma of the esophagus are related to timing of death due to recurrence
    Lagarde, SM; Boer, JD; Kate, FJ
  • Anastomotic leak increases distant recurrence and long-term mortality after curative resection for colonic cancer: a nationwide cohort study
    Krarup, PM; Nordholm-Carstensen, A; Jorgensen, LN
  • Postoperative complications after transthoracic esophagectomy for cancer of the esophagus and gastroesophageal junction are correlated with early cancer recurrence: role of systematic grading of complications using the modified Clavien classification
    Lerut, T; Moons, J; Coosemans, W
  • Evaluation of POSSUM in patients with oesophageal cancer undergoing resection
    Zafirellis, KD; Fountoulakis, A; Dolan, K
  • Cervical or thoracic anastomosis after esophagectomy for cancer: a systematic review and meta-analysis
    Biere, SS; Maas, KW; Cuesta, MA
  • Cancer-related inflammation
    Mantovani, A; Allavena, P; Sica, A
  • Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses
    Goldfarb, Y; Sorski, L; Benish, M
  • The immunobiology of cancer immunosurveillance and immunoediting
    Dunn, GP; Old, LJ; Schreiber, RD
  • Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey
    Dindo, D; Demartines, N; Clavien, PA
  • Japanese classification of esophageal cancer
  • Investigation of the freely-available easy-to-use software “EZR” (Easy R) for medical statistics
    Kanda, Y
  • CEA-Antigen and SCC-Antigen mRNA expression in peripheral blood predict hematogenous recurrence after resection in patients with esophageal cancer
    Tanaka, K; Yano, M; Motoori, M
  • Reduced incidence of nodal micrometastasis after major response to neoadjuvant chemoradiation in locally advanced esophageal cancer
    Prenzel, KL; König, A; Schneider, PM
  • Which is the optimal response criteria for evaluating preoperative treatment in esophageal cancer: RECIST or Histology?
    Kurokawa, Y; Shibata, T; Ando, N
  • Prognostic significance of histopathological tumor regression after neoadjuvant chemotherapy in esophageal adenocarcinomas
    Langer, R; Ott, K; Feith, M
  • Posttherapy pathologic stage predicts survival in patients with esophageal carcinoma receiving preoperative chemoradiation
    Chirieac, LR; Swisher, SG; Ajani, JA
  • Tumor regression grading of gastrointestinal carcinomas after neoadjuvant treatment
    Thies, S; Langer, R
  • Three-field vs twofield lymph node dissection for esophageal cancer: a meta-analysis
    Ma, GW; Situ, DR; Ma, QL
  • Thoracic esophageal carcinoma above the carina: a more formidable adversary?
    Kato, H; Tachimori, Y; Watanabe, H

You’re reading a free preview. Subscribe to read the entire article.

Try 2 weeks free now

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

or browse the journals available

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

Sign up
for free
Start 14 day
Free Trial