As a new proposal, natural tears collected from the Schirmer strips were studied using surface pressure-area, π-A, isotherms obtained with the Langmuir technique. Parameters such as limit surface pressure, πlimit, elastic modulus at the maximum, CS −1 max, and surface pressure at the maximum, πmax, were correlated with clinical tests, such as the Schirmer (SCH) and the tear film breakup-time (TFBUT) tests. The analysis from the chi-square test indicates dependence between the SCH test and the type of isotherms with a value of P < 0.05. A moderate Pearson correlation coefficient with statistical significance (P < 0.05) between the values of the SCH test and the πlimit was obtained. On the other hand, a low Pearson correlation coefficient with no statistical significance (P > 0.05) between the values of the TFBUT test and the πlimit was obtained. Additionally, considering only the isotherms classified as good, moderate Pearson correlation coefficients with statistical significance (P < 0.05) between the values of the TFBUT test and πlimit or πmax can be obtained. This study shows that the isotherms obtained with the Langmuir technique correlate well with the tear secretion, and when the later is moderate or good, the isotherm parameters afford information about the tear film stability and the behaviour of the tear lipids.
BioNanoScience – Springer Journals
Published: Jan 26, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera