development activity have been expended to ﬁnd new ceramic bone substitutes for the treatment of bone defects. However in many cases the drawback of synthethic bone substitutes are the slow graft incorporation and remodelling into the host bone. The purpose of this study was to analyze the kinetics of resorption and new bone formation of new calcium sulfate (CaSO )/calcium phosphate (CaPO ) bio- 4 4 ceramic engineered to enhance its bone forming properties. We prospectively evaluated the results of a series of 15 hips with osteonecrosis of the femoral head (ONFH) treated at with core decompression and injection of the CaSO /CaPO 4 4 composite. In all hips, a quantitative computed tomography (QTC) scan was taken within one week after the surgery, at 12 months, 2 years and ﬁnally with a minimum of 4 years follow-up. The mean HU in the immediate post-operative period was 1445 (Range 1388–1602); At one year the mean HU strongly decrease at 556.6 HU (P < 0.01); The mean HU at 2 years follow-up further decreased to 475.1. The mean HU at 4 years was unchanged. The quantitative and qualitative CT scan data of this series indicates that the CaSO -CaPO ceramic composite
Journal of Materials Science: Materials in Medicine – Springer Journals
Published: Aug 7, 2017
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