The Interaction of the rad201Gene with Genes mei-9and mei-41in Germline Cells of DrosophilaFemales

The Interaction of the rad201Gene with Genes mei-9and mei-41in Germline Cells of DrosophilaFemales The effect of Drosophilamutation rad201 G1together with mutations mei-41 D5and mei-9 aon the sensitivity of oocytes to induction of dominant lethals (DLs) was studied. To this end, the frequencies of spontaneous and gamma-radiation-induced DLs in consecutive egg batches of females carrying double or single mutations were estimated. Since the effects of the mutations examined are expressed only at the previtellogenetic stages of oogenesis, only newly hatched (0–5-hour-old) females, whose oocytes did not develop farther than stage 7, were irradiated. The results obtained indicated that in intact and irradiated oocytes of double mutants mei-9 a rad201 G1and mei-41 D5 rad201 G1, mutation rad201 G1epistatically suppresses the mutations of the both meigenes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

The Interaction of the rad201Gene with Genes mei-9and mei-41in Germline Cells of DrosophilaFemales

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Publisher
Kluwer Academic Publishers-Plenum Publishers
Copyright
Copyright © 2001 by MAIK “Nauka/Interperiodica”
Subject
Biomedicine; Human Genetics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1023/A:1016742808860
Publisher site
See Article on Publisher Site

Abstract

The effect of Drosophilamutation rad201 G1together with mutations mei-41 D5and mei-9 aon the sensitivity of oocytes to induction of dominant lethals (DLs) was studied. To this end, the frequencies of spontaneous and gamma-radiation-induced DLs in consecutive egg batches of females carrying double or single mutations were estimated. Since the effects of the mutations examined are expressed only at the previtellogenetic stages of oogenesis, only newly hatched (0–5-hour-old) females, whose oocytes did not develop farther than stage 7, were irradiated. The results obtained indicated that in intact and irradiated oocytes of double mutants mei-9 a rad201 G1and mei-41 D5 rad201 G1, mutation rad201 G1epistatically suppresses the mutations of the both meigenes.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Oct 16, 2004

References

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