Ann Surg Oncol (2018) 25:2091–2097 https://doi.org/10.1245/s10434-018-6497-3 O R I G IN AL ARTI CL E – HE AD A N D N ECK O N C OLO G Y The Impact of Metronomic Adjuvant Chemotherapy in Patients with Advanced Oral Cancer 1 2 3 4,5,6 Ming-Yu Hsieh, MD , Gene Chen , Dun-Cheng Chang, PhD , Su-Yu Chien, RPh, MS , and Mu-Kuan Chen, MD, 1,7 MSc, PhD Department of Otorhinolaryngology-Head and Neck Surgery, Changhua Christian Hospital, Changhua, Taiwan; 2 3 Southridge School, Surrey, BC, Canada; Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan; 4 5 Department of Pharmacy, Changhua Christian Hospital, Changhua, Taiwan; College of Health Sciences, Chang Jung 6 7 Christian University, Tainan, Taiwan; Center for General Education, Mingdao University, Changhua, Taiwan; Changhua Christian Medical Centre, Changhua, Taiwan ABSTRACT also showing a decreased distant metastasis rate. Tegafur- Background. This study evaluated the efﬁcacy of tegafur- uracil treatment is a useful, effective, and well-tolerated uracil for advanced oral cancer. anticancer treatment for advanced oral cancer. Methods. From January 2008 to December 2013, clinical data from 356 patients with stage III or IV oral squamous The global incidence of head and neck cancer is cell carcinoma who received curative
Annals of Surgical Oncology – Springer Journals
Published: May 2, 2018
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