Eur J Clin Pharmacol (2017) 73:1055–1069 DOI 10.1007/s00228-017-2269-4 REVIEW The impact of exposure to antidepressant medications during pregnancy on neonatal outcomes: a review of retrospective database cohort studies 1,2 3 4 5,11 Casey R. Tak & Kathleen M. Job & Katie Schoen-Gentry & Sarah C. Campbell & 6,7 8 1,9 10 Patrick Carroll & Maged Costantine & Diana Brixner & Angela K. Birnbaum & 2,3,11 Catherine M. T. Sherwin Received: 23 February 2017 /Accepted: 22 May 2017 /Published online: 9 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract date through July 15, 2016. Studies with a retrospective cohort Introduction Concerns with prescription antidepressant use in design and conducted in national/regional medical or claims pregnant women have instigated the examination of potential databases were included. Searched outcomes included pre- associations between fetal exposure to antidepressant medica- term delivery, congenital malformations, low birth weight, tion and outcomes including preterm delivery, congenital small for gestational age, persistent pulmonary hypertension malformations, perinatal and post-natal adverse events, persis- of the newborn, and other select adverse events comprising tent pulmonary hypertension, and mortality. The retrospective low Apgar score (5 min), convulsions/seizures, respiratory cohort model is an often utilized study design. The objective distress/problems, fetal mortality, and
European Journal of Clinical Pharmacology – Springer Journals
Published: Jun 9, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud