The impact of exposure to antidepressant medications during pregnancy on neonatal outcomes: a review of retrospective database cohort studies

The impact of exposure to antidepressant medications during pregnancy on neonatal outcomes: a... Eur J Clin Pharmacol (2017) 73:1055–1069 DOI 10.1007/s00228-017-2269-4 REVIEW The impact of exposure to antidepressant medications during pregnancy on neonatal outcomes: a review of retrospective database cohort studies 1,2 3 4 5,11 Casey R. Tak & Kathleen M. Job & Katie Schoen-Gentry & Sarah C. Campbell & 6,7 8 1,9 10 Patrick Carroll & Maged Costantine & Diana Brixner & Angela K. Birnbaum & 2,3,11 Catherine M. T. Sherwin Received: 23 February 2017 /Accepted: 22 May 2017 /Published online: 9 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract date through July 15, 2016. Studies with a retrospective cohort Introduction Concerns with prescription antidepressant use in design and conducted in national/regional medical or claims pregnant women have instigated the examination of potential databases were included. Searched outcomes included pre- associations between fetal exposure to antidepressant medica- term delivery, congenital malformations, low birth weight, tion and outcomes including preterm delivery, congenital small for gestational age, persistent pulmonary hypertension malformations, perinatal and post-natal adverse events, persis- of the newborn, and other select adverse events comprising tent pulmonary hypertension, and mortality. The retrospective low Apgar score (5 min), convulsions/seizures, respiratory cohort model is an often utilized study design. The objective distress/problems, fetal mortality, and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Clinical Pharmacology Springer Journals

The impact of exposure to antidepressant medications during pregnancy on neonatal outcomes: a review of retrospective database cohort studies

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Biomedicine; Pharmacology/Toxicology
ISSN
0031-6970
eISSN
1432-1041
D.O.I.
10.1007/s00228-017-2269-4
Publisher site
See Article on Publisher Site

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