Mammalian Genome 9, 246-249 (1998). Mammalian Genome Incorporating Moore Genome © Springer-Verlag New York Inc. 1998 The human ortholog of rhesus mannose-binding protein-A gene is an expressed pseudogene that localizes to Chromosome 10 Ning Guo, l Tirsit Mogues, l Stanislawa Weremowicz, 2 Cynthia C. Morton, 3 Kedarnath N. Sastry l 'Department of Pathology, K726, Boston University School of Medicine, 80 East Concord Street, Boston, Massachusetts 02118, USA 2Department of Pathology, Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA 'Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA Received: 13 September 1997 / Accepted: 12 November 1997 Mannose-binding protein (MBP, also known as Mannan- or Man- pressed at low levels in human liver, but appears to be a pseudo- nose-binding lectin) is a member of the collectin family of proteins gene transcript. Further, we have characterized the exon-intron (Turner 1996). Isolation and characterization of cDNAs from liver organization of this human pseudogene named MBLJPI, and lo- tissues of a number of mammals have provided important infor- calized it to Chromosome (Chr) 10. mation about the primary structure of MBP. A single polypeptide Two
Mammalian Genome – Springer Journals
Published: Mar 21, 2009
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