The hemoglobin-deficit mutation is located on mouse Chromosome 19

The hemoglobin-deficit mutation is located on mouse Chromosome 19 Short Communications Incorporating Mouse Genome Mammalian Genome 9, 666–667 (1998). © Springer-Verlag New York Inc. 1998 Michael L. Bloom, Karen L. Simon-Stoos, Meghann E. Mabon National Institutes of Health, National Heart, Lung, and Blood Institute, Bldg. 10, Room 7C 118, Bethesda, Maryland 20892, USA Received: 9 January 1998 / Accepted: 6 April 1998 Hemoglobin-deficit (gene symbol hbd) occurred as a spontaneous apparent phenotypic difference was the zpp levels. Mice with a mutation in an unknown inbred agouti stock (Scheufler 1969). value of over 100 mmol/mol heme were scored as anemic. The Homozygous mice were mated to another inbred strain known as distributions of zpp, mcv, and hgb were clearly bimodal, which AB/Jena-Halle. Heterozygous mice with a black coat color and a made it possible to assign unambiguously a phenotype to each white belly spot were selected for subsequent matings. The strain mouse. The phenotyping was further confirmed by analysis of the was imported into The Jackson Laboratory in 1980, and the mu- histograms produced from the rbc counting taken with a Coulter tation was subsequently backcrossed onto the C57BL/6J back- Counter (not shown). Affected and normal mice were easily dis- ground for more than 16 generations. tinguished by the Mammalian Genome Springer Journals

The hemoglobin-deficit mutation is located on mouse Chromosome 19

Loading next page...
Copyright © 1998 by Springer-Verlag New York Inc.
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial