Access the full text.
Sign up today, get DeepDyve free for 14 days.
A. Anderson, A. Anderson, K. Christoff, Iris Stappen, D. Panitz, D. Ghahremani, G. Glover, J. Gabrieli, N. Sobel (2003)
Dissociated neural representations of intensity and valence in human olfactionNature Neuroscience, 6
J. Whitfield, G. Zhu, P. Madden, M. Neale, A. Heath, N. Martin (2004)
The genetics of alcohol intake and of alcohol dependence.Alcoholism, clinical and experimental research, 28 8
J. Ma, W. Catterall, T. Scheuer (1997)
Persistent Sodium Currents through Brain Sodium Channels Induced by G Protein βγ SubunitsNeuron, 19
J. Belknap, N. Belknap, J. Berg, R. Coleman (1977)
Preabsorptive vs. postabsorptive control of ethanol intake in C57BL/6J and DBA/2J miceBehavior Genetics, 7
A. Mantovani, C. Garlanda, A. Doni, B. Bottazzi (2007)
Pentraxins in Innate Immunity: From C-Reactive Protein to the Long Pentraxin PTX3Journal of Clinical Immunology, 28
A. Bergen, Xiaohong Yang, Yan Bai, M. Beerman, A. Goldstein, L. Goldin (2003)
Genomic regions linked to alcohol consumption in the Framingham Heart StudyBMC Genetics, 4
Sanjiv Bhave, Cheryl Hornbaker, T. Phang, L. Saba, R. Lapadat, K. Kechris, J. Gaydos, D. McGoldrick, A. Dolbey, S. Leach, Brian Soriano, Allison Ellington, Eric Ellington, K. Jones, J. Mangion, J. Belknap, Robert Williams, L. Hunter, P. Hoffman, B. Tabakoff (2007)
The PhenoGen Informatics website: tools for analyses of complex traitsBMC Genetics, 8
F. Chaillan, F. Roman, B. Soumireu-Mourat, (1996)
Modulation of synaptic plasticity in the hippocampus and piriform cortex by physiologically meaningful olfactory cues in an olfactory association taskJournal of Physiology-Paris, 90
L. Rodriguez, R. Plomin, D. Blizard, B. Jones, G. Mcclearn (1994)
Alcohol acceptance, preference, and sensitivity in mice. I. Quantitative genetic analysis using BXD recombinant inbred strains.Alcoholism, clinical and experimental research, 18 6
A. Goldin (2003)
Mechanisms of sodium channel inactivationCurrent Opinion in Neurobiology, 13
D. Newlin, B. Hotchkiss, W. Cox, F. Rauscher, T. Li (1989)
Autonomic and subjective responses to alcohol stimuli with appropriate control stimuli.Addictive behaviors, 14 6
W. Mcbride, Ting-kai Li (1998)
Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents.Critical reviews in neurobiology, 12 4
H. Kalant, A. Leblanc, R. Gibbins (1971)
Tolerance to, and dependence on, some non-opiate psychotropic drugs.Pharmacological reviews, 23 3
L. Buck (2006)
Smell and Taste : The Chemical Senses
G. Edwards, E. Marshall, C. Cook (2003)
The Treatment of Drinking Problems: The alcohol dependence syndrome
K. Gerrow, A. El-Husseini (2007)
Receptors Look Outward: Revealing Signals That Bring Excitation to SynapsesScience's STKE, 2007
M. Mantegazza, F. Yu, A. Powell, J. Clare, W. Catterall, T. Scheuer (2005)
Molecular Determinants for Modulation of Persistent Sodium Current by G-Protein βγ SubunitsThe Journal of Neuroscience, 25
A. Kampov-Polevoy, O. Kasheffskaya, J. Sinclair (1990)
Initial acceptance of ethanol: gustatory factors and patterns of alcohol drinking.Alcohol, 7 2
M. Mantegazza, F. Yu, A. Powell, J. Clare, W. Catterall, T. Scheuer (2005)
Molecular determinants for modulation of persistent sodium current by G-protein betagamma subunits.The Journal of neuroscience : the official journal of the Society for Neuroscience, 25 13
E. Lander, D. Botstein (1989)
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.Genetics, 121 1
R. Ritzmann, B. Tabakoff (1976)
Body temperature in mice: a quantitative measure of alcohol tolerance and physical dependence.The Journal of pharmacology and experimental therapeutics, 199 1
(2005)
International statistical classification of diseases and health related problems
V. Kapoor, F. Subach, V. Kozlov, A. Grudinin, V. Verkhusha, W. Telford (2007)
SNPs matter: impact on detection of differential expression
J. He, Susana Neves, J. Jordan, R. Iyengar (2006)
Role of the Go/i signaling network in the regulation of neurite outgrowth.Canadian journal of physiology and pharmacology, 84 7
A. Hishimoto, Qing-Rong Liu, T. Drgon, O. Pletnikova, D. Walther, Xuguang Zhu, J. Troncoso, G. Uhl (2007)
Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms.Human molecular genetics, 16 23
L. Saba, Sanjiv Bhave, N. Grahame, P. Bice, R. Lapadat, J. Belknap, P. Hoffman, B. Tabakoff (2006)
Candidate genes and their regulatory elements: alcohol preference and toleranceMammalian Genome, 17
E. Chesler, Lu Lu, S. Shou, Yanhua Qu, Jing Gu, Jintao Wang, H. Hsu, J. Mountz, Nicole Baldwin, M. Langston, D. Threadgill, K. Manly, Robert Williams (2005)
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system functionNature Genetics, 37
G. Sia, J. Béïque, Gavin Rumbaugh, Richard Cho, P. Worley, R. Huganir (2007)
Interaction of the N-Terminal Domain of the AMPA Receptor GluR4 Subunit with the Neuronal Pentraxin NP1 Mediates GluR4 Synaptic RecruitmentNeuron, 55
(2006)
Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington’s disease transgenic mice
F. Anda, Giulia Pollarolo, Jorge Silva, P. Camoletto, F. Feiguin, C. Dotti (2005)
Centrosome localization determines neuronal polarityNature, 436
M. Zutter, B. Edelson (2007)
The α2β1 integrin: A novel collectin/C1q receptorImmunobiology, 212
M. Reid, F. Flammino, A. Starosta, J. Palamar, J. Franck (2006)
Physiological and subjective responding to alcohol cue exposure in alcoholics and control subjects: evidence for appetitive respondingJournal of Neural Transmission, 113
Ting-kai Li, B. Hewitt, B. Grant (2007)
The Alcohol Dependence Syndrome, 30 years later: a commentary. the 2006 H. David Archibald lecture.Addiction, 102 10
Megan Mulligan, I. Ponomarev, R. Hitzemann, J. Belknap, B. Tabakoff, R. Harris, J. Crabbe, Y. Blednov, N. Grahame, T. Phillips, D. Finn, P. Hoffman, V. Iyer, G. Koob, S. Bergeson (2006)
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.Proceedings of the National Academy of Sciences of the United States of America, 103 16
M. Cowen, E. Djouma, A. Lawrence (2005)
The Metabotropic Glutamate 5 Receptor Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine Reduces Ethanol Self-Administration in Multiple Strains of Alcohol-Preferring Rats and Regulates Olfactory Glutamatergic SystemsJournal of Pharmacology and Experimental Therapeutics, 315
P. Maccioni, A. Orrù, A. Korkosz, G. Gessa, M. Carai, G. Colombo, P. Bieńkowski (2007)
Cue-induced reinstatement of ethanol seeking in Sardinian alcohol-preferring rats.Alcohol, 41 1
J. Schroeder, D. Overstreet, C. Hodge (2005)
The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) ratsPsychopharmacology, 179
Qing-Rong Liu, T. Drgon, Catherine Johnson, D. Walther, Judith Hess, G. Uhl (2006)
Addiction molecular genetics: 639,401 SNP whole genome association identifies many “cell adhesion” genesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 141B
N. Grahame, T. Li, L. Lumeng (1999)
Selective Breeding for High and Low Alcohol Preference in MiceBehavior Genetics, 29
Dyke McEwen, R. Koenekoop, H. Khanna, Paul Jenkins, I. Lopez, A. Swaroop, J. Martens (2007)
Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neuronsProceedings of the National Academy of Sciences, 104
V. Fedulov, Christopher Rex, D. Simmons, L. Palmer, C. Gall, G. Lynch (2007)
Evidence That Long-Term Potentiation Occurs within Individual Hippocampal Synapses during LearningThe Journal of Neuroscience, 27
A. Field (2001)
Meta-analysis of correlation coefficients: a Monte Carlo comparison of fixed- and random-effects methods.Psychological methods, 6 2
D. Wahlsten, A. Bachmanov, D. Finn, J. Crabbe (2006)
Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decadesProceedings of the National Academy of Sciences, 103
C. Tsui, N. Copeland, D. Gilbert, N. Jenkins, C. Barnes, P. Worley (1996)
Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity, 16
M. Enoch, D. Goldman (2001)
The genetics of alcoholism and alcohol abuseCurrent Psychiatry Reports, 3
Genomics of alcohol preference
M. Zutter, B. Edelson (2007)
The alpha2beta1 integrin: a novel collectin/C1q receptor.Immunobiology, 212 4-5
I. Guerrini, C. Cook, W. Kest, A. Devitgh, A. McQuillin, D. Curtis, H. Gurling (2005)
Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2BMC Genetics, 6
Sanjiv Bhave, P. Hoffman, N. Lassen, V. Vasiliou, L. Saba, R. Deitrich, B. Tabakoff (2006)
Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice.Alcoholism, clinical and experimental research, 30 10
Elizabeth Chiang, B. Strowbridge (2007)
Diversity of neural signals mediated by multiple, burst-firing mechanisms in rat olfactory tubercle neurons.Journal of neurophysiology, 98 5
J. Liang, M. Cockett, X. Khawaja (1998)
Immunohistochemical localization of G protein beta1, beta2, beta3, beta4, beta5, and gamma3 subunits in the adult rat brain.Journal of neurochemistry, 71 1
L. Hedges, Jack Vevea (1998)
Fixed- and random-effects models in meta-analysis.Psychological Methods, 3
Claire Martin, Jennifer Beshel, L. Kay (2007)
An olfacto-hippocampal network is dynamically involved in odor-discrimination learning.Journal of neurophysiology, 98 4
E. Gould (2007)
How widespread is adult neurogenesis in mammals?Nature Reviews Neuroscience, 8
N. Yoneyama, J. Crabbe, M. Ford, Andrea Murillo, D. Finn (2008)
Voluntary ethanol consumption in 22 inbred mouse strains.Alcohol, 42 3
Jin-jun Liang, M. Cockett, X. Khawaja (1998)
Immunohistochemical Localization of G Protein β1, β2, β3, β4, β5, and γ3 Subunits in the Adult Rat BrainJournal of Neurochemistry, 71
J. Connolly, T. Tully (1998)
Integrins: A role for adhesion molecules in olfactory memoryCurrent Biology, 8
Y. Benjamini, Y. Hochberg (1995)
Controlling the false discovery rate: a practical and powerful approach to multiple testingJournal of the royal statistical society series b-methodological, 57
Roberto Meléndez, L. Middaugh, P. Kalivas (2006)
Development of an alcohol deprivation and escalation effect in C57BL/6J mice.Alcoholism, clinical and experimental research, 30 12
A. Bachmanov, S. Kiefer, J. Molina, M. Tordoff, V. Duffy, L. Bartoshuk, J. Mennella (2003)
Chemosensory factors influencing alcohol perception, preferences, and consumption.Alcoholism, clinical and experimental research, 27 2
P. Visscher, Robin Thompson, C. Haley (1996)
Confidence intervals in QTL mapping by bootstrapping.Genetics, 143 2
E. Lein, M. Hawrylycz, Nancy Ao, M. Ayres, Amy Bensinger, Amy Bernard, A. Boe, M. Boguski, Kevin Brockway, Emi Byrnes, Lin Chen, Li Chen, Tsuey-Ming Chen, Mei Chin, Jimmy Chong, Brian Crook, Aneta Czaplinska, Chinh Dang, S. Datta, N. Dee, Aimee Desaki, Tsega Desta, Ellen Diep, Tim Dolbeare, M. Donelan, Hong-wei Dong, J. Dougherty, Ben Duncan, Amanda Ebbert, G. Eichele, Lili Estin, C. Faber, B. Facer, Rick Fields, S. Fischer, Tim Fliss, C. Frensley, Sabrina Gates, Katie Glattfelder, K. Halverson, Matthew Hart, J. Hohmann, Maureen Howell, Darren Jeung, Rebecca Johnson, Patrick Karr, Reena Kawal, Jolene Kidney, Rachel Knapik, C. Kuan, J. Lake, A. Laramee, Kirk Larsen, C. Lau, Tracy Lemon, Agnes Liang, Y. Liu, Lon Luong, Jesse Michaels, J. Morgan, Rebecca Morgan, M. Mortrud, Nerick Mosqueda, Lydia Ng, Randy Ng, Geralyn Orta, C. Overly, Tu Pak, Sheana Parry, S. Pathak, Owen Pearson, R. Puchalski, Z. Riley, Hannah Rockett, S. Rowland, J. Royall, M. Ruiz, N. Sarno, K. Schaffnit, N. Shapovalova, Taz Sivisay, C. Slaughterbeck, Simon Smith, Kimberly Smith, Bryan Smith, Andrew Sodt, Nick Stewart, K. Stumpf, S. Sunkin, Madhavi Sutram, Angelene Tam, C. Teemer, C. Thaller, C. Thompson, Lee Varnam, A. Visel, Ray Whitlock, Paul Wohnoutka, Crissa Wolkey, V. Wong, M. Wood, M. Yaylaoglu, R. Young, Brian Youngstrom, Xuefeng Yuan, Bin Zhang, T. Zwingman, Allan Jones (2007)
Genome-wide atlas of gene expression in the adult mouse brainNature, 445
J. Ma, W. Catterall, T. Scheuer (1997)
Persistent sodium currents through brain sodium channels induced by G protein betagamma subunits.Neuron, 19 2
Andrew Bergen, Andrea Baccarelli, Timothy McDaniel, Kenneth Kuhn, Ruth Pfeiffer, Jerry Kakol, Patrick Bender, Kevin Jacobs, Bernice Packer, S. Chanock, Meredith Yeager (2007)
cis sequence effects on gene expressionBMC Genomics, 8
V. Matys, O. Kel-Margoulis, E. Fricke, I. Liebich, S. Land, A. Barre-Dirrie, I. Reuter, D. Chekmenev, M. Krull, K. Hornischer, N. Voss, P. Stegmaier, B. Lewicki-Potapov, H. Saxel, A. Kel, E. Wingender (2005)
TRANSFAC® and its module TRANSCompel®: transcriptional gene regulation in eukaryotesNucleic Acids Research, 34
E. Kandel, James Schwartz, Thomas Jessell (1981)
Principles of Neural Science
Holden Higginbotham, J. Gleeson (2007)
The centrosome in neuronal developmentTrends in Neurosciences, 30
Tina Grieco, J. Malhotra, Chunling Chen, L. Isom, I. Raman (2005)
Open-Channel Block by the Cytoplasmic Tail of Sodium Channel β4 as a Mechanism for Resurgent Sodium CurrentNeuron, 45
(1994)
Diagnostic and statistical manual of mental disorders
Searches for the identity of genes that influence the levels of alcohol consumption by humans and other animals have often been driven by presupposition of the importance of particular gene products in determining positively or negatively reinforcing effects of ethanol. We have taken an unbiased approach and performed a meta-analysis across three types of mouse populations to correlate brain gene expression with levels of alcohol intake. Our studies, using filtering procedures based on QTL analysis, produced a list of eight candidate genes with highly heritable expression, which could explain a significant amount of the variance in alcohol preference in mice. Using the Allen Brain Atlas for gene expression, we noted that the candidate genes’ expression was localized to the olfactory and limbic areas as well as to the orbitofrontal cortex. Informatics techniques and pathway analysis illustrated the role of the candidate genes in neuronal migration, differentiation, and synaptic remodeling. The importance of olfactory cues, learning and memory formation (Pavlovian conditioning), and cortical executive function, for regulating alcohol intake by animals (including humans), is discussed.
Mammalian Genome – Springer Journals
Published: Jun 19, 2008
Access the full text.
Sign up today, get DeepDyve free for 14 days.